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- W2024386543 abstract "This study was conducted to observe the effect of the growth hormone (GH)/insulin-like growth factor-1(/IGF-1) axis on leptin and feed intake of 15 Holstein calves in three groups. One group was fed a normal diet (control); the second group, with high nutrition after low feeding with bovine growth hormone (bGH), and a third group, without high nutrition (saline) after low feeding. Each group was intramuscularly (i.m.) injected daily with bovine GH (200 µg kg -1 d -1 ) or saline solution for 10 d. No significant differences were found in the concentrations of plasma leptin over time for a 24-h period. Plasma leptin was decreased in both saline and GH groups during low and high nutrition regimes, respectively, while IGF-1 levels increased for both nutrition regimes (P < 0.05). With GH treatment during refeeding periods (P < 0.05), leptin levels increased and feed intake decreased; however, the plasma leptin levels slightly decreased with GH treatment during low feeding periods. The plasma IGF-1 concentration increased with GH administration during normal and refeeding periods (P < 0.05). These results indicate that the response of plasma leptin levels to GH varied according to the nutritional condition. In addition, the GH/IGF-1-induced increase in leptin production during the refeeding period may serve as a signal to reduce the feed intake or to increase dramatically after feed restriction in cattle. Key words: Feed intake, growth hormone, leptin, insulin-like growth factor-1, Holstein calves" @default.
- W2024386543 created "2016-06-24" @default.
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- W2024386543 date "2006-06-01" @default.
- W2024386543 modified "2023-10-16" @default.
- W2024386543 title "The responseof plasma leptin and feed intake to growth hormone administration in Holstein calves with different planes of nutrition" @default.
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- W2024386543 doi "https://doi.org/10.4141/a05-009" @default.
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