Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024391188> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2024391188 endingPage "166" @default.
- W2024391188 startingPage "159" @default.
- W2024391188 abstract "Following aerosol-challenge of nonimmune calves with bovine herpesvirus type-1 (BHV-1) the levels of 2′,5′ oligoadenylate (2-5A) synthetase in peripheral blood mononuclear cells (PBML) increased significantly to peak 4–5 days after BHV-1 infection. This corresponded temporally to the period of highest susceptibility to secondary bacterial infection. Ten days post virus infection, the enzyme levels had returned to baseline values. Aerosol challenge with bacteria (Pasteurella haemolytica) did not induce 2-5A synthetase activity in PBML, neither did it influence the kinetics of 2-5A synthetase induction by virus infection during a dual viral–bacterial infection. Pretreatment of animals with bovine recombinant interferons (IFNs) 0–96 h prior to virus challenge curtailed the viral infection and thus reduced the levels of 2-5A synthetase induced by endogenously produced IFN. A relationship between 2-5A synthetase levels on day 5 post virus infection and clinical outcome of the dual infection was noted. Moreover, the high 2-5A synthetase levels could be correlated with low plasma Zn levels, another indicator of clinical respiratory disease. These results indicate that these two parameters, 2-5A synthetase and plasma Zn, in combination have potential prognostic value in viral–bacterial infections of the respiratory tract." @default.
- W2024391188 created "2016-06-24" @default.
- W2024391188 creator A5003424164 @default.
- W2024391188 creator A5047258184 @default.
- W2024391188 creator A5053235127 @default.
- W2024391188 creator A5076980991 @default.
- W2024391188 creator A5079330921 @default.
- W2024391188 date "1989-04-01" @default.
- W2024391188 modified "2023-09-25" @default.
- W2024391188 title "2′,5′ Oligoadenylate Synthetase Activity in Bovine Peripheral Blood Mononuclear Cells Following Bovine Herpesvirus Type-1-Induced Respiratory Disease: A Prognostic Indicator?" @default.
- W2024391188 cites W17016290 @default.
- W2024391188 cites W181308494 @default.
- W2024391188 cites W1911631514 @default.
- W2024391188 cites W1978939305 @default.
- W2024391188 cites W2010304591 @default.
- W2024391188 cites W2038758352 @default.
- W2024391188 cites W2045023213 @default.
- W2024391188 cites W2055548560 @default.
- W2024391188 cites W2062854784 @default.
- W2024391188 cites W2075858230 @default.
- W2024391188 cites W2093801171 @default.
- W2024391188 cites W2109775693 @default.
- W2024391188 cites W2112770600 @default.
- W2024391188 cites W2112834292 @default.
- W2024391188 cites W2142956358 @default.
- W2024391188 cites W2316021304 @default.
- W2024391188 cites W2328841790 @default.
- W2024391188 cites W2413282018 @default.
- W2024391188 cites W6917144 @default.
- W2024391188 cites W70074729 @default.
- W2024391188 doi "https://doi.org/10.1089/jir.1989.9.159" @default.
- W2024391188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2715670" @default.
- W2024391188 hasPublicationYear "1989" @default.
- W2024391188 type Work @default.
- W2024391188 sameAs 2024391188 @default.
- W2024391188 citedByCount "7" @default.
- W2024391188 countsByYear W20243911882017 @default.
- W2024391188 crossrefType "journal-article" @default.
- W2024391188 hasAuthorship W2024391188A5003424164 @default.
- W2024391188 hasAuthorship W2024391188A5047258184 @default.
- W2024391188 hasAuthorship W2024391188A5053235127 @default.
- W2024391188 hasAuthorship W2024391188A5076980991 @default.
- W2024391188 hasAuthorship W2024391188A5079330921 @default.
- W2024391188 hasConcept C105702510 @default.
- W2024391188 hasConcept C137061746 @default.
- W2024391188 hasConcept C159047783 @default.
- W2024391188 hasConcept C181199279 @default.
- W2024391188 hasConcept C202751555 @default.
- W2024391188 hasConcept C203014093 @default.
- W2024391188 hasConcept C2522874641 @default.
- W2024391188 hasConcept C2779644171 @default.
- W2024391188 hasConcept C534529494 @default.
- W2024391188 hasConcept C55493867 @default.
- W2024391188 hasConcept C86803240 @default.
- W2024391188 hasConcept C89423630 @default.
- W2024391188 hasConceptScore W2024391188C105702510 @default.
- W2024391188 hasConceptScore W2024391188C137061746 @default.
- W2024391188 hasConceptScore W2024391188C159047783 @default.
- W2024391188 hasConceptScore W2024391188C181199279 @default.
- W2024391188 hasConceptScore W2024391188C202751555 @default.
- W2024391188 hasConceptScore W2024391188C203014093 @default.
- W2024391188 hasConceptScore W2024391188C2522874641 @default.
- W2024391188 hasConceptScore W2024391188C2779644171 @default.
- W2024391188 hasConceptScore W2024391188C534529494 @default.
- W2024391188 hasConceptScore W2024391188C55493867 @default.
- W2024391188 hasConceptScore W2024391188C86803240 @default.
- W2024391188 hasConceptScore W2024391188C89423630 @default.
- W2024391188 hasIssue "2" @default.
- W2024391188 hasLocation W20243911881 @default.
- W2024391188 hasLocation W20243911882 @default.
- W2024391188 hasOpenAccess W2024391188 @default.
- W2024391188 hasPrimaryLocation W20243911881 @default.
- W2024391188 hasRelatedWork W1568848974 @default.
- W2024391188 hasRelatedWork W1875171869 @default.
- W2024391188 hasRelatedWork W1976124441 @default.
- W2024391188 hasRelatedWork W2056473717 @default.
- W2024391188 hasRelatedWork W2103264367 @default.
- W2024391188 hasRelatedWork W2125797431 @default.
- W2024391188 hasRelatedWork W2126152546 @default.
- W2024391188 hasRelatedWork W2269754317 @default.
- W2024391188 hasRelatedWork W2278836635 @default.
- W2024391188 hasRelatedWork W2313414779 @default.
- W2024391188 hasVolume "9" @default.
- W2024391188 isParatext "false" @default.
- W2024391188 isRetracted "false" @default.
- W2024391188 magId "2024391188" @default.
- W2024391188 workType "article" @default.