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- W2024391568 abstract "Clopidogrel is an inactive prodrug that is converted into the active metabolites by the cytochrome P-450 (CYP) system. The impact of coadministration of statin and clopidogrel on platelet inhibition is controversial, which may result from assessment during early period statin use, differences in assays used, and the selection of high posttreatment platelet reactivity (HPPR) and normal responders to clopidogrel. During chronic phase of coadministration of statin and clopidogrel, the influence of CYP3A4 vs non-CYP3A4 metabolized statin on platelet inhibition has not been evaluated." @default.
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- W2024391568 date "2010-04-01" @default.
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- W2024391568 title "AS-252: The Impact of Non-Cytochrome 3A4 Metabolized Statin in Patients with High Post-Clopidogrel Platelet Reactivity: The Results of the ACCEL-SWITCH Study" @default.
- W2024391568 doi "https://doi.org/10.1016/j.amjcard.2010.01.305" @default.
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