FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024392088> ?p ?o ?g. }

• W2024392088 endingPage "e46" @default.
• W2024392088 startingPage "e46" @default.
• W2024392088 abstract "The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used theMonodelphis domestica (gray short-tailed opossum) sequence to construct the first map of a marsupial major histocompatibility complex (MHC). The MHC is the most gene-dense region of the mammalian genome and is critical to immunity and reproductive success. The marsupial MHC bridges the phylogenetic gap between the complex MHC of eutherian mammals and the minimal essential MHC of birds. Here we show that the opossum MHC is gene dense and complex, as in humans, but shares more organizational features with non-mammals. The Class I genes have amplified within the Class II region, resulting in a unique Class I/II region. We present a model of the organization of the MHC in ancestral mammals and its elaboration during mammalian evolution. The opossum genome, together with other extant genomes, reveals the existence of an ancestral “immune supercomplex” that contained genes of both types of natural killer receptors together with antigen processing genes and MHC genes." @default.
• W2024392088 created "2016-06-24" @default.
• W2024392088 creator A5001135422 @default.
• W2024392088 creator A5003786277 @default.
• W2024392088 creator A5006160118 @default.
• W2024392088 creator A5013182680 @default.
• W2024392088 creator A5029455059 @default.
• W2024392088 creator A5034070636 @default.
• W2024392088 creator A5035243414 @default.
• W2024392088 creator A5037664752 @default.
• W2024392088 creator A5042618575 @default.
• W2024392088 creator A5045056236 @default.
• W2024392088 creator A5054939935 @default.
• W2024392088 creator A5055102276 @default.
• W2024392088 creator A5059620673 @default.
• W2024392088 creator A5067719457 @default.
• W2024392088 creator A5069294286 @default.
• W2024392088 creator A5073806855 @default.
• W2024392088 creator A5077269033 @default.
• W2024392088 creator A5086218353 @default.
• W2024392088 date "2006-01-31" @default.
• W2024392088 modified "2023-10-11" @default.
• W2024392088 title "Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex" @default.
• W2024392088 cites W1497954397 @default.
• W2024392088 cites W1522242792 @default.
• W2024392088 cites W1547891533 @default.
• W2024392088 cites W1579320766 @default.
• W2024392088 cites W1584763538 @default.
• W2024392088 cites W1634772899 @default.
• W2024392088 cites W1672359460 @default.
• W2024392088 cites W1788981306 @default.
• W2024392088 cites W1845578368 @default.
• W2024392088 cites W1967253926 @default.
• W2024392088 cites W1968705217 @default.
• W2024392088 cites W1975571037 @default.
• W2024392088 cites W1978406065 @default.
• W2024392088 cites W1979567369 @default.
• W2024392088 cites W1985857568 @default.
• W2024392088 cites W1991112256 @default.
• W2024392088 cites W1995610172 @default.
• W2024392088 cites W1995765989 @default.
• W2024392088 cites W1997387817 @default.
• W2024392088 cites W1999169677 @default.
• W2024392088 cites W2005441733 @default.
• W2024392088 cites W2008595821 @default.
• W2024392088 cites W2023711349 @default.
• W2024392088 cites W2032449149 @default.
• W2024392088 cites W2041877620 @default.
• W2024392088 cites W2046353247 @default.
• W2024392088 cites W2047675109 @default.
• W2024392088 cites W2050030472 @default.
• W2024392088 cites W2050721511 @default.
• W2024392088 cites W2055043387 @default.
• W2024392088 cites W2067714729 @default.
• W2024392088 cites W2077128825 @default.
• W2024392088 cites W2079044333 @default.
• W2024392088 cites W2094567316 @default.
• W2024392088 cites W2097751983 @default.
• W2024392088 cites W2120622979 @default.
• W2024392088 cites W2136145671 @default.
• W2024392088 cites W2137270049 @default.
• W2024392088 cites W2141847640 @default.
• W2024392088 cites W2145477956 @default.
• W2024392088 cites W2149769193 @default.
• W2024392088 cites W2157447805 @default.
• W2024392088 cites W2160056003 @default.
• W2024392088 cites W2166143536 @default.
• W2024392088 cites W2166187656 @default.
• W2024392088 cites W2170069789 @default.
• W2024392088 cites W2170632052 @default.
• W2024392088 cites W2318785836 @default.
• W2024392088 doi "https://doi.org/10.1371/journal.pbio.0040046" @default.
• W2024392088 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1351924" @default.
• W2024392088 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16435885" @default.
• W2024392088 hasPublicationYear "2006" @default.
• W2024392088 type Work @default.
• W2024392088 sameAs 2024392088 @default.
• W2024392088 citedByCount "139" @default.
• W2024392088 countsByYear W20243920882012 @default.
• W2024392088 countsByYear W20243920882013 @default.
• W2024392088 countsByYear W20243920882014 @default.
• W2024392088 countsByYear W20243920882015 @default.
• W2024392088 countsByYear W20243920882016 @default.
• W2024392088 countsByYear W20243920882017 @default.
• W2024392088 countsByYear W20243920882018 @default.
• W2024392088 countsByYear W20243920882019 @default.
• W2024392088 countsByYear W20243920882020 @default.
• W2024392088 countsByYear W20243920882021 @default.
• W2024392088 countsByYear W20243920882022 @default.
• W2024392088 countsByYear W20243920882023 @default.
• W2024392088 crossrefType "journal-article" @default.
• W2024392088 hasAuthorship W2024392088A5001135422 @default.
• W2024392088 hasAuthorship W2024392088A5003786277 @default.
• W2024392088 hasAuthorship W2024392088A5006160118 @default.
• W2024392088 hasAuthorship W2024392088A5013182680 @default.
• W2024392088 hasAuthorship W2024392088A5029455059 @default.
• W2024392088 hasAuthorship W2024392088A5034070636 @default.
• W2024392088 hasAuthorship W2024392088A5035243414 @default.

• next