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• W2024395029 endingPage "4970" @default.
• W2024395029 startingPage "4970" @default.
• W2024395029 abstract "Layer-by-Layer (LbL) approach was applied for the encapsulation of antileishmanial drugs viz. chalcones (3-mB-4′-HC and 3-DC-4′-HC) to study their release properties at pH 7.4 from a polyelectrolyte self assembled multilayer thin film. The LbL self assembly was achieved by alternate adsorption of oppositely charged polyelectrolytes, poly(styrene-4-sulfonic acid) sodium salt (PSS) and poly(diallyldimethylammonium) chloride (PDADMAC) on planar quartz substrate. The growth of the multilayer self assembly as well as loading and release of the drugs were studied by UV-Visible spectroscopy. Both the chalcones, 3-mB-4′-HC and 3-DC-4′-HC have shown controlled and sustained release up to 224 and 824 minutes respectively. Kinetic fitting of the data confirmed that the process of drug release from the self assembly followed pseudo second order kinetics (R2 ≥ 0.99)." @default.
• W2024395029 created "2016-06-24" @default.
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• W2024395029 date "2014-01-01" @default.
• W2024395029 modified "2023-09-28" @default.
• W2024395029 title "Controlled drug delivery of antileishmanial chalcones from Layer-by-Layer (LbL) self assembled PSS/PDADMAC thin films" @default.
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• W2024395029 doi "https://doi.org/10.1039/c3ra44611e" @default.
• W2024395029 hasPublicationYear "2014" @default.
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