FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024396919> ?p ?o ?g. }

• W2024396919 endingPage "1285" @default.
• W2024396919 startingPage "1281" @default.
• W2024396919 abstract "Background B-mode ultrasound studies indicate that hyperhomocysteinemia is associated with preclinical structural and functional arterial abnormalities. This study was designed to evaluate the effect of elevated plasma homocysteine levels on coronary flow reserve (CFR). Methods A total of 20 healthy subjects aged 41 ± 7 years were studied on 2 separate days, a week apart, before and after methionine load (100 mg/kg of body weight) or placebo in a double-blind crossover study. At each visit, homocysteine levels were measured by high performance liquid chromatography and CFR was determined by transthoracic Doppler echocardiography. Results After methionine load, plasma homocysteine increased from 10.7 ± 2.8 μmol/L to 30.4 ± 5.1 μmol/L (P < .0001) and CFR decreased from 3.0 ± 0.4 to 2.3 ± 0.3 (P < .001). CFR was inversely related to postload homocysteine levels (r = −0.21, P = .02). After placebo, there was no change in CFR. Conclusion In asymptomatic adults, acute hyperhomocysteinemia is associated with a significant reduction in CFR. B-mode ultrasound studies indicate that hyperhomocysteinemia is associated with preclinical structural and functional arterial abnormalities. This study was designed to evaluate the effect of elevated plasma homocysteine levels on coronary flow reserve (CFR). A total of 20 healthy subjects aged 41 ± 7 years were studied on 2 separate days, a week apart, before and after methionine load (100 mg/kg of body weight) or placebo in a double-blind crossover study. At each visit, homocysteine levels were measured by high performance liquid chromatography and CFR was determined by transthoracic Doppler echocardiography. After methionine load, plasma homocysteine increased from 10.7 ± 2.8 μmol/L to 30.4 ± 5.1 μmol/L (P < .0001) and CFR decreased from 3.0 ± 0.4 to 2.3 ± 0.3 (P < .001). CFR was inversely related to postload homocysteine levels (r = −0.21, P = .02). After placebo, there was no change in CFR. In asymptomatic adults, acute hyperhomocysteinemia is associated with a significant reduction in CFR." @default.
• W2024396919 created "2016-06-24" @default.
• W2024396919 creator A5013174325 @default.
• W2024396919 creator A5016753594 @default.
• W2024396919 creator A5019612051 @default.
• W2024396919 creator A5025979537 @default.
• W2024396919 creator A5042459633 @default.
• W2024396919 creator A5044611925 @default.
• W2024396919 creator A5052663922 @default.
• W2024396919 creator A5055873388 @default.
• W2024396919 creator A5063838502 @default.
• W2024396919 creator A5067526328 @default.
• W2024396919 date "2004-12-01" @default.
• W2024396919 modified "2023-09-27" @default.
• W2024396919 title "Effect of acute hyperhomocysteinemia on coronary flow reserve in healthy adults" @default.
• W2024396919 cites W1963628789 @default.
• W2024396919 cites W1966292733 @default.
• W2024396919 cites W1967944238 @default.
• W2024396919 cites W1988516817 @default.
• W2024396919 cites W1991736423 @default.
• W2024396919 cites W1993145269 @default.
• W2024396919 cites W1997596609 @default.
• W2024396919 cites W1999382514 @default.
• W2024396919 cites W2003720627 @default.
• W2024396919 cites W2020542094 @default.
• W2024396919 cites W2024847137 @default.
• W2024396919 cites W2028917578 @default.
• W2024396919 cites W2037604424 @default.
• W2024396919 cites W2050744333 @default.
• W2024396919 cites W2051220082 @default.
• W2024396919 cites W2075771143 @default.
• W2024396919 cites W2088493953 @default.
• W2024396919 cites W2092973272 @default.
• W2024396919 cites W2104373067 @default.
• W2024396919 cites W2107611836 @default.
• W2024396919 cites W2124378690 @default.
• W2024396919 cites W2126048757 @default.
• W2024396919 cites W2128476850 @default.
• W2024396919 cites W2145899271 @default.
• W2024396919 cites W2146029011 @default.
• W2024396919 cites W2162886683 @default.
• W2024396919 cites W2169939099 @default.
• W2024396919 cites W2317172136 @default.
• W2024396919 cites W2332685851 @default.
• W2024396919 cites W2342150662 @default.
• W2024396919 cites W4234437490 @default.
• W2024396919 cites W4256578596 @default.
• W2024396919 doi "https://doi.org/10.1016/j.echo.2004.07.011" @default.
• W2024396919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15562267" @default.
• W2024396919 hasPublicationYear "2004" @default.
• W2024396919 type Work @default.
• W2024396919 sameAs 2024396919 @default.
• W2024396919 citedByCount "13" @default.
• W2024396919 countsByYear W20243969192013 @default.
• W2024396919 countsByYear W20243969192016 @default.
• W2024396919 countsByYear W20243969192022 @default.
• W2024396919 countsByYear W20243969192023 @default.
• W2024396919 crossrefType "journal-article" @default.
• W2024396919 hasAuthorship W2024396919A5013174325 @default.
• W2024396919 hasAuthorship W2024396919A5016753594 @default.
• W2024396919 hasAuthorship W2024396919A5019612051 @default.
• W2024396919 hasAuthorship W2024396919A5025979537 @default.
• W2024396919 hasAuthorship W2024396919A5042459633 @default.
• W2024396919 hasAuthorship W2024396919A5044611925 @default.
• W2024396919 hasAuthorship W2024396919A5052663922 @default.
• W2024396919 hasAuthorship W2024396919A5055873388 @default.
• W2024396919 hasAuthorship W2024396919A5063838502 @default.
• W2024396919 hasAuthorship W2024396919A5067526328 @default.
• W2024396919 hasConcept C126322002 @default.
• W2024396919 hasConcept C126894567 @default.
• W2024396919 hasConcept C142724271 @default.
• W2024396919 hasConcept C158846371 @default.
• W2024396919 hasConcept C164705383 @default.
• W2024396919 hasConcept C204787440 @default.
• W2024396919 hasConcept C27081682 @default.
• W2024396919 hasConcept C2776523773 @default.
• W2024396919 hasConcept C2777090595 @default.
• W2024396919 hasConcept C2777910003 @default.
• W2024396919 hasConcept C2778707443 @default.
• W2024396919 hasConcept C71924100 @default.
• W2024396919 hasConcept C87813604 @default.
• W2024396919 hasConceptScore W2024396919C126322002 @default.
• W2024396919 hasConceptScore W2024396919C126894567 @default.
• W2024396919 hasConceptScore W2024396919C142724271 @default.
• W2024396919 hasConceptScore W2024396919C158846371 @default.
• W2024396919 hasConceptScore W2024396919C164705383 @default.
• W2024396919 hasConceptScore W2024396919C204787440 @default.
• W2024396919 hasConceptScore W2024396919C27081682 @default.
• W2024396919 hasConceptScore W2024396919C2776523773 @default.
• W2024396919 hasConceptScore W2024396919C2777090595 @default.
• W2024396919 hasConceptScore W2024396919C2777910003 @default.
• W2024396919 hasConceptScore W2024396919C2778707443 @default.
• W2024396919 hasConceptScore W2024396919C71924100 @default.
• W2024396919 hasConceptScore W2024396919C87813604 @default.
• W2024396919 hasIssue "12" @default.
• W2024396919 hasLocation W20243969191 @default.
• W2024396919 hasLocation W20243969192 @default.
• W2024396919 hasOpenAccess W2024396919 @default.

• next