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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024397313> ?p ?o ?g. }

• W2024397313 abstract "Hemoglobin chain synthesis during leukemic processes has been studied on patients having fetal hemoglobin. All cases showed the following abnormalities : (1) a relatively increased synthesis of the beta chain ; (2) an important increase of the free dimeric precursors pool, with, most of the time, a predominance of alpha chain. If the first point suggests an alpha-thalassemia feature, the presence of free alpha chains shows evidence for a more complex mechanism not only due to a decrease of messenger RNA. The hypothesis of a clonal disorder could neither be demonstrated nor ruled out. The observed abnormalities could be due to a defect in a alpha chain depending regulation mechanism." @default.
• W2024397313 created "2016-06-24" @default.
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• W2024397313 date "1975-04-01" @default.
• W2024397313 modified "2023-09-23" @default.
• W2024397313 title "Abnormal hemoglobin synthesis in some leukemic patients" @default.
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• W2024397313 doi "https://doi.org/10.1016/s0300-9084(75)80111-8" @default.
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