FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024402521> ?p ?o ?g. }

• W2024402521 endingPage "123" @default.
• W2024402521 startingPage "112" @default.
• W2024402521 abstract "We investigated the effect of immune challenge with LPS in both control rats and rats with adjuvant-induced arthritis (AA). Fourteen day-AA rats showed the expected activation of the hypothalamic-pituitary adrenal axis associated with increases in vasopressin mRNA and paradoxical decreases in corticotropin-releasing hormone (CRH) mRNA in parvocellular neurons of the hypothalamic paraventricular nucleus (PVN). However, following LPS there was an increase in both CRH and vasopressin mRNA in the PVN. Neither control rats nor rats with AA had measurable plasma levels of IL-6, but plasma levels of IL-1beta were 2.7-fold higher in AA animals. Following LPS injection both IL-1beta and IL-6 increased more markedly in AA than in control rats. Neither controls nor AA rats expressed IL-1beta or IL-6 mRNA in the brain. However, following LPS these were induced in the subfornical organ, choroid plexus, and median eminence of both groups of animals. The areas expressing IL-1b mRNA were larger in the AA animals and exhibited a punctate pattern throughout the brain parenchyma and PVN. These data reveal an increased peripheral and central immunological response to LPS during the chronic inflammatory process of AA, providing a mechanism through which inflammatory disease can influence the response to a novel immunological challenge." @default.
• W2024402521 created "2016-06-24" @default.
• W2024402521 creator A5010779419 @default.
• W2024402521 creator A5012163019 @default.
• W2024402521 creator A5013747215 @default.
• W2024402521 creator A5017571758 @default.
• W2024402521 creator A5024913732 @default.
• W2024402521 creator A5025600506 @default.
• W2024402521 creator A5078320006 @default.
• W2024402521 date "2002-11-01" @default.
• W2024402521 modified "2023-10-16" @default.
• W2024402521 title "Hypothalamic Pituitary Adrenal Axis and Immune Responses to Endotoxin in Rats with Chronic Adjuvant-Induced Arthritis" @default.
• W2024402521 cites W1485026357 @default.
• W2024402521 cites W1509473298 @default.
• W2024402521 cites W1549436051 @default.
• W2024402521 cites W1971659823 @default.
• W2024402521 cites W1986130500 @default.
• W2024402521 cites W1986362058 @default.
• W2024402521 cites W1989306597 @default.
• W2024402521 cites W1997596092 @default.
• W2024402521 cites W1999275802 @default.
• W2024402521 cites W2001455948 @default.
• W2024402521 cites W2002339478 @default.
• W2024402521 cites W2007528432 @default.
• W2024402521 cites W2010547730 @default.
• W2024402521 cites W2011223523 @default.
• W2024402521 cites W2013524799 @default.
• W2024402521 cites W2022658269 @default.
• W2024402521 cites W2031934304 @default.
• W2024402521 cites W2036994812 @default.
• W2024402521 cites W2046560245 @default.
• W2024402521 cites W2047036493 @default.
• W2024402521 cites W2054908842 @default.
• W2024402521 cites W2068392981 @default.
• W2024402521 cites W2069465895 @default.
• W2024402521 cites W2081973677 @default.
• W2024402521 cites W2082566286 @default.
• W2024402521 cites W2082941372 @default.
• W2024402521 cites W2088159839 @default.
• W2024402521 cites W2096305168 @default.
• W2024402521 cites W2099106836 @default.
• W2024402521 cites W2114608871 @default.
• W2024402521 cites W2120658378 @default.
• W2024402521 cites W2128426900 @default.
• W2024402521 cites W2140298451 @default.
• W2024402521 cites W2163277460 @default.
• W2024402521 cites W2181566246 @default.
• W2024402521 cites W2343187620 @default.
• W2024402521 cites W4230886030 @default.
• W2024402521 cites W4234244228 @default.
• W2024402521 cites W4235095653 @default.
• W2024402521 cites W4241586906 @default.
• W2024402521 cites W4243948583 @default.
• W2024402521 cites W4244363958 @default.
• W2024402521 cites W4251853815 @default.
• W2024402521 doi "https://doi.org/10.1006/exnr.2002.8022" @default.
• W2024402521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12460613" @default.
• W2024402521 hasPublicationYear "2002" @default.
• W2024402521 type Work @default.
• W2024402521 sameAs 2024402521 @default.
• W2024402521 citedByCount "21" @default.
• W2024402521 countsByYear W20244025212012 @default.
• W2024402521 countsByYear W20244025212013 @default.
• W2024402521 countsByYear W20244025212014 @default.
• W2024402521 countsByYear W20244025212018 @default.
• W2024402521 countsByYear W20244025212020 @default.
• W2024402521 countsByYear W20244025212021 @default.
• W2024402521 crossrefType "journal-article" @default.
• W2024402521 hasAuthorship W2024402521A5010779419 @default.
• W2024402521 hasAuthorship W2024402521A5012163019 @default.
• W2024402521 hasAuthorship W2024402521A5013747215 @default.
• W2024402521 hasAuthorship W2024402521A5017571758 @default.
• W2024402521 hasAuthorship W2024402521A5024913732 @default.
• W2024402521 hasAuthorship W2024402521A5025600506 @default.
• W2024402521 hasAuthorship W2024402521A5078320006 @default.
• W2024402521 hasConcept C126322002 @default.
• W2024402521 hasConcept C134018914 @default.
• W2024402521 hasConcept C203014093 @default.
• W2024402521 hasConcept C2776370428 @default.
• W2024402521 hasConcept C2776538271 @default.
• W2024402521 hasConcept C2777003273 @default.
• W2024402521 hasConcept C2778458438 @default.
• W2024402521 hasConcept C2779067335 @default.
• W2024402521 hasConcept C2780352252 @default.
• W2024402521 hasConcept C2780841215 @default.
• W2024402521 hasConcept C529278444 @default.
• W2024402521 hasConcept C71315377 @default.
• W2024402521 hasConcept C71924100 @default.
• W2024402521 hasConcept C8891405 @default.
• W2024402521 hasConceptScore W2024402521C126322002 @default.
• W2024402521 hasConceptScore W2024402521C134018914 @default.
• W2024402521 hasConceptScore W2024402521C203014093 @default.
• W2024402521 hasConceptScore W2024402521C2776370428 @default.
• W2024402521 hasConceptScore W2024402521C2776538271 @default.
• W2024402521 hasConceptScore W2024402521C2777003273 @default.
• W2024402521 hasConceptScore W2024402521C2778458438 @default.
• W2024402521 hasConceptScore W2024402521C2779067335 @default.
• W2024402521 hasConceptScore W2024402521C2780352252 @default.

• next