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• W2024408058 abstract "Our purpose was to compare the level of expression of both type 1 and type 2 cyclooxygenase genes before and after labor and to localize their expression within the fetal membranes.The sites of type 2 and type 1 cyclooxygenase messenger ribonucleic acid synthesis were identified with in situ hybridization. Expression of both types 1 and 2 cyclooxygenase was studied by reverse transcriptase polymerase chain reaction.Cyclooxygenase type 2 and type 1 expression was localized within the amniotic epithelium and amniotic mesoderm. Type 1 but not type 2 enzyme was also expressed in the chorionic mesoderm. Expression of the type 2 enzyme was significantly increased with the onset of labor. Type 1 enzyme expression did not significantly change with labor.It is most likely that it is the inducible type 2 cyclooxygenase enzyme that mediates the increase in prostaglandin synthesis in amnion with the onset of labor." @default.
• W2024408058 created "2016-06-24" @default.
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• W2024408058 date "1995-01-01" @default.
• W2024408058 modified "2023-10-14" @default.
• W2024408058 title "Expression of cyclooxygenase types 1 and 2 in human fetal membranes at term" @default.
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• W2024408058 doi "https://doi.org/10.1016/0002-9378(95)90087-x" @default.
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