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• W2024421889 abstract "The IMPROVE™ study was a 26-week, multinational, open-label, non-randomized study, carried out in 11 countries. To evaluate the safety and efficacy of biphasic insulin aspart 30 (BIAsp 30) in patients with type 2 diabetes under routine clinical practice. There were no prescribed procedures for this study except for the collection of data. Data obtained at baseline and Week 26 in patients from the Gulf region is presented. From the Gulf region, 1613 patients (61% males) were enrolled with a mean age of 50.5 years and a mean BMI of 30.4 kg/m2. The majority of the patients (57.0%) were treated with OAD only, while 34.3% patients were previously treated with insulin ±OAD and 8.7% were treatment naive. After 26 weeks of treatment, the mean HbA1c was reduced by 1.4% from 9.3% at baseline to 7.9% at Week 26. The mean FBG was reduced by 66.6 mg/dL from 212.4 mg/dL at baseline to 145.8 mg/dL at Week 26. No major hypoglycaemic episodes were reported as SADRs during the study. The rate of major hypoglycaemic episodes was reduced from 0.13 episodes/patient year at baseline to 0.05 episodes/patient year at Week 26. A lower risk of minor hypoglycaemia was also observed. Body weight was reduced by 0.6 kg from 85.4 kg at baseline to 84.7 kg at Week 26. BIAsp 30 improved glycaemic control without increasing the risk of hypoglycaemic episodes and weight gain after 26 weeks’ treatment in patients with type 2 diabetes from the Gulf region." @default.
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• W2024421889 date "2010-08-01" @default.
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• W2024421889 title "Safety and efficacy of switching to biphasic insulin aspart 30/70 (BIAsp 30) under the routine diabetic care in patients with type 2 diabetes: The IMPROVE™ observational study in the Gulf region" @default.
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• W2024421889 doi "https://doi.org/10.1016/j.ijdm.2010.05.001" @default.
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