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• W2024423048 startingPage "467" @default.
• W2024423048 abstract "<i>Aims:</i> To determine areas of atrophy in patients that are associated with caregiver burden. <i>Methods:</i> We measured caregiver burden, dementia and neuropsychiatric scores in 22 patients with corticobasal syndrome (CBS) and 25 with frontotemporal dementia (FTD), and in 14 healthy controls. We used voxel-based morphometry to correlate caregiver burden with gray matter loss. <i>Results:</i> Increased dementia and behavioral disturbances contributed to higher burden scores in CBS patients, while behavioral disturbances alone significantly affected burden scores in frontal-variant FTD (FTD-fv) patients. In CBS patients, caregiver burden scores correlated with atrophy in left inferior and middle temporal gyri. <i>Conclusions:</i> Caregivers of FTD-fv patients had significantly higher burden scores than caregivers of CBS patients. Damage to areas important in semantic knowledge appears critical in increased burden for CBS caregivers." @default.
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• W2024423048 date "2008-01-01" @default.
• W2024423048 modified "2023-10-12" @default.
• W2024423048 title "Neural Correlates of Caregiver Burden in Cortical Basal Syndrome and Frontotemporal Dementia" @default.
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• W2024423048 doi "https://doi.org/10.1159/000167268" @default.
• W2024423048 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2596937" @default.
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