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• W2024430051 abstract "A specialized kinetic analysis of real-time hyperpolarized [1,1,2,2-D4, 1-(13)C]choline (13)C-magnetic resonance spectroscopy enabled the determination of initial rates of metabolic enzyme activity (choline oxidase), enzyme-substrate affinity (Km), and inhibition. In a clinical MRI scanner, metabolite levels lower than 16 μM were detected at a temporal resolution of 1 s." @default.
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• W2024430051 date "2014-01-01" @default.
• W2024430051 modified "2023-09-27" @default.
• W2024430051 title "Direct enzyme–substrate affinity determination by real-time hyperpolarized13C-MRS" @default.
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• W2024430051 doi "https://doi.org/10.1039/c4cc05418k" @default.
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