FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024431133> ?p ?o ?g. }

• W2024431133 abstract "Abstract Background Lipocalins are a large and diverse family of small, mostly extracellular proteins implicated in many important functions. This family has been studied in bacteria, invertebrate and vertebrate animals but little is known about these proteins in plants. We recently reported the identification and molecular characterization of the first true lipocalins from plants, including the Apolipoprotein D ortholog AtTIL identified in the plant model Arabidopsis thaliana . This study aimed to determine its physiological role in planta . Results Our results demonstrate that the AtTIL lipocalin is involved in modulating tolerance to oxidative stress. AtTIL knock-out plants are very sensitive to sudden drops in temperature and paraquat treatment, and dark-grown plants die shortly after transfer to light. These plants accumulate a high level of hydrogen peroxide and other ROS, which causes an oxidative stress that is associated with a reduction in hypocotyl growth and sensitivity to light. Complementation of the knock-out plants with the AtTIL cDNA restores the normal phenotype. On the other hand, overexpression enhances tolerance to stress caused by freezing, paraquat and light. Moreover, this overexpression delays flowering and maintains leaf greenness. Microarray analyses identified several differentially-regulated genes encoding components of oxidative stress and energy balance. Conclusion This study provides the first functional evidence that a plant lipocalin is involved in modulating tolerance to oxidative stress. These findings are in agreement with recently published data showing that overexpression of ApoD enhances tolerance to oxidative stress and increases life span in mice and Drosophila. Together, the three papers strongly support a similar function of lipocalins in these evolutionary-distant species." @default.
• W2024431133 created "2016-06-24" @default.
• W2024431133 creator A5024032639 @default.
• W2024431133 creator A5040607109 @default.
• W2024431133 creator A5069728436 @default.
• W2024431133 creator A5075376190 @default.
• W2024431133 date "2008-07-31" @default.
• W2024431133 modified "2023-10-11" @default.
• W2024431133 title "The plant Apolipoprotein D ortholog protects Arabidopsis against oxidative stress" @default.
• W2024431133 cites W1501460217 @default.
• W2024431133 cites W1502362372 @default.
• W2024431133 cites W2015093208 @default.
• W2024431133 cites W2020311598 @default.
• W2024431133 cites W2022966294 @default.
• W2024431133 cites W2029876010 @default.
• W2024431133 cites W2036815314 @default.
• W2024431133 cites W2049158367 @default.
• W2024431133 cites W2054686729 @default.
• W2024431133 cites W2066541482 @default.
• W2024431133 cites W2087269822 @default.
• W2024431133 cites W2095643322 @default.
• W2024431133 cites W2098115340 @default.
• W2024431133 cites W2101136171 @default.
• W2024431133 cites W2116122104 @default.
• W2024431133 cites W2121418654 @default.
• W2024431133 cites W2123844599 @default.
• W2024431133 cites W2131780511 @default.
• W2024431133 cites W2137057701 @default.
• W2024431133 cites W2147961708 @default.
• W2024431133 cites W2149945633 @default.
• W2024431133 cites W2153522847 @default.
• W2024431133 cites W2158367220 @default.
• W2024431133 cites W2166379545 @default.
• W2024431133 cites W2170989872 @default.
• W2024431133 cites W4241639017 @default.
• W2024431133 doi "https://doi.org/10.1186/1471-2229-8-86" @default.
• W2024431133 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2527315" @default.
• W2024431133 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18671872" @default.
• W2024431133 hasPublicationYear "2008" @default.
• W2024431133 type Work @default.
• W2024431133 sameAs 2024431133 @default.
• W2024431133 citedByCount "100" @default.
• W2024431133 countsByYear W20244311332012 @default.
• W2024431133 countsByYear W20244311332013 @default.
• W2024431133 countsByYear W20244311332014 @default.
• W2024431133 countsByYear W20244311332015 @default.
• W2024431133 countsByYear W20244311332016 @default.
• W2024431133 countsByYear W20244311332017 @default.
• W2024431133 countsByYear W20244311332018 @default.
• W2024431133 countsByYear W20244311332019 @default.
• W2024431133 countsByYear W20244311332020 @default.
• W2024431133 countsByYear W20244311332021 @default.
• W2024431133 countsByYear W20244311332022 @default.
• W2024431133 countsByYear W20244311332023 @default.
• W2024431133 crossrefType "journal-article" @default.
• W2024431133 hasAuthorship W2024431133A5024032639 @default.
• W2024431133 hasAuthorship W2024431133A5040607109 @default.
• W2024431133 hasAuthorship W2024431133A5069728436 @default.
• W2024431133 hasAuthorship W2024431133A5075376190 @default.
• W2024431133 hasBestOaLocation W20244311331 @default.
• W2024431133 hasConcept C104317684 @default.
• W2024431133 hasConcept C127716648 @default.
• W2024431133 hasConcept C143065580 @default.
• W2024431133 hasConcept C188082640 @default.
• W2024431133 hasConcept C20299238 @default.
• W2024431133 hasConcept C2775988993 @default.
• W2024431133 hasConcept C2776151105 @default.
• W2024431133 hasConcept C2776527163 @default.
• W2024431133 hasConcept C2779491563 @default.
• W2024431133 hasConcept C54355233 @default.
• W2024431133 hasConcept C55493867 @default.
• W2024431133 hasConcept C86803240 @default.
• W2024431133 hasConcept C95444343 @default.
• W2024431133 hasConceptScore W2024431133C104317684 @default.
• W2024431133 hasConceptScore W2024431133C127716648 @default.
• W2024431133 hasConceptScore W2024431133C143065580 @default.
• W2024431133 hasConceptScore W2024431133C188082640 @default.
• W2024431133 hasConceptScore W2024431133C20299238 @default.
• W2024431133 hasConceptScore W2024431133C2775988993 @default.
• W2024431133 hasConceptScore W2024431133C2776151105 @default.
• W2024431133 hasConceptScore W2024431133C2776527163 @default.
• W2024431133 hasConceptScore W2024431133C2779491563 @default.
• W2024431133 hasConceptScore W2024431133C54355233 @default.
• W2024431133 hasConceptScore W2024431133C55493867 @default.
• W2024431133 hasConceptScore W2024431133C86803240 @default.
• W2024431133 hasConceptScore W2024431133C95444343 @default.
• W2024431133 hasIssue "1" @default.
• W2024431133 hasLocation W20244311331 @default.
• W2024431133 hasLocation W20244311332 @default.
• W2024431133 hasLocation W20244311333 @default.
• W2024431133 hasLocation W20244311334 @default.
• W2024431133 hasOpenAccess W2024431133 @default.
• W2024431133 hasPrimaryLocation W20244311331 @default.
• W2024431133 hasRelatedWork W109070002 @default.
• W2024431133 hasRelatedWork W1594012662 @default.
• W2024431133 hasRelatedWork W2006745274 @default.
• W2024431133 hasRelatedWork W2077106292 @default.
• W2024431133 hasRelatedWork W2106134872 @default.
• W2024431133 hasRelatedWork W2269421989 @default.
• W2024431133 hasRelatedWork W2355042192 @default.

• next