FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024432944> ?p ?o ?g. }

• W2024432944 abstract "Introduction Clinical outcome is an important determinant of programme success. This study aims to evaluate patients’ baseline characteristics as well as level of care associated with lost to follow‐up (LTFU) and mortality of patients on antiretroviral treatment (ART). Methods Retrospective cohort study using routine service data of adult patients initiated on ART in 2007 in 10 selected hospitals in Nigeria. We captured data using an electronic medical record system and analyzed using Stata. Outcome measures were probability of being alive and retained in care at 12, 24 and 36 months on ART. Potential predictors associated with time to mortality and time to LTFU were assessed using competing risks regression models. Results After 12 months on therapy, 85% of patients were alive and on ART. Survival decreased to 81.2% and 76.1% at 24 and 36 months, respectively. Median CD4 count for patients at ART start, 12, 18 and 24 months were 152 (interquartile range, IQR: 75 to 242), 312 (IQR: 194 to 450), 344 (IQR: 227 to 501) and 372 (IQR: 246 to 517) cells/µl, respectively. Competing risk regression showed that patients’ baseline characteristics significantly associated with LTFU were male (adjusted sub‐hazard ratio, sHR=1.24 [95% CI: 1.08 to 1.42]), ambulatory functional status (adjusted sHR=1.25 [95% CI: 1.01 to 1.54]), World Health Organization (WHO) clinical Stage II (adjusted sHR=1.31 [95% CI: 1.08 to 1.59]) and care in a secondary site (adjusted sHR=0.76 [95% CI: 0.66 to 0.87]). Those associated with mortality include CD4 count <50 cells/µl (adjusted sHR=2.84 [95% CI: 1.20 to 6.71]), WHO clinical Stage III (adjusted sHR=2.67 [95% CI: 1.26 to 5.65]) and Stage IV (adjusted sHR=5.04 [95% CI: 1.93 to 13.16]) and care in a secondary site (adjusted sHR=2.21 [95% CI: 1.30 to 3.77]). Conclusions Mortality was associated with advanced HIV disease and care in secondary facilities. Earlier initiation of therapy and strengthening systems in secondary level facilities may improve retention and ultimately contribute to better clinical outcomes." @default.
• W2024432944 created "2016-06-24" @default.
• W2024432944 creator A5009546678 @default.
• W2024432944 creator A5011304225 @default.
• W2024432944 creator A5013548945 @default.
• W2024432944 creator A5015999389 @default.
• W2024432944 creator A5017528412 @default.
• W2024432944 creator A5027160124 @default.
• W2024432944 creator A5035599848 @default.
• W2024432944 creator A5045479933 @default.
• W2024432944 creator A5049031267 @default.
• W2024432944 creator A5084219685 @default.
• W2024432944 date "2012-04-01" @default.
• W2024432944 modified "2023-10-15" @default.
• W2024432944 title "Patients’ demographic and clinical characteristics and level of care associated with lost to follow-up and mortality in adult patients on first-line ART in Nigerian hospitals" @default.
• W2024432944 cites W1531725059 @default.
• W2024432944 cites W1737354777 @default.
• W2024432944 cites W1964622370 @default.
• W2024432944 cites W1970713740 @default.
• W2024432944 cites W1971334912 @default.
• W2024432944 cites W1983537547 @default.
• W2024432944 cites W1990161832 @default.
• W2024432944 cites W2001017566 @default.
• W2024432944 cites W2001316390 @default.
• W2024432944 cites W2001792255 @default.
• W2024432944 cites W2004293828 @default.
• W2024432944 cites W2017793579 @default.
• W2024432944 cites W2018551422 @default.
• W2024432944 cites W2028463034 @default.
• W2024432944 cites W2031368727 @default.
• W2024432944 cites W2038981426 @default.
• W2024432944 cites W2053998858 @default.
• W2024432944 cites W2058699555 @default.
• W2024432944 cites W2059065586 @default.
• W2024432944 cites W2065293221 @default.
• W2024432944 cites W2068392998 @default.
• W2024432944 cites W2072159217 @default.
• W2024432944 cites W2082077320 @default.
• W2024432944 cites W2082372399 @default.
• W2024432944 cites W2090624329 @default.
• W2024432944 cites W2097345834 @default.
• W2024432944 cites W2099306766 @default.
• W2024432944 cites W2106837439 @default.
• W2024432944 cites W2121894695 @default.
• W2024432944 cites W2124801504 @default.
• W2024432944 cites W2127578660 @default.
• W2024432944 cites W2137523454 @default.
• W2024432944 cites W2137850028 @default.
• W2024432944 cites W2139894829 @default.
• W2024432944 cites W2146329405 @default.
• W2024432944 cites W2146390081 @default.
• W2024432944 cites W2159572649 @default.
• W2024432944 cites W2160888326 @default.
• W2024432944 cites W2160992219 @default.
• W2024432944 cites W2163477848 @default.
• W2024432944 cites W2167371517 @default.
• W2024432944 cites W2168841389 @default.
• W2024432944 cites W2169980588 @default.
• W2024432944 cites W2171141994 @default.
• W2024432944 cites W2207308994 @default.
• W2024432944 cites W2318289184 @default.
• W2024432944 cites W2340851790 @default.
• W2024432944 doi "https://doi.org/10.7448/ias.15.2.17424" @default.
• W2024432944 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3494164" @default.
• W2024432944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23010378" @default.
• W2024432944 hasPublicationYear "2012" @default.
• W2024432944 type Work @default.
• W2024432944 sameAs 2024432944 @default.
• W2024432944 citedByCount "36" @default.
• W2024432944 countsByYear W20244329442012 @default.
• W2024432944 countsByYear W20244329442013 @default.
• W2024432944 countsByYear W20244329442014 @default.
• W2024432944 countsByYear W20244329442015 @default.
• W2024432944 countsByYear W20244329442016 @default.
• W2024432944 countsByYear W20244329442017 @default.
• W2024432944 countsByYear W20244329442018 @default.
• W2024432944 countsByYear W20244329442019 @default.
• W2024432944 countsByYear W20244329442020 @default.
• W2024432944 countsByYear W20244329442021 @default.
• W2024432944 countsByYear W20244329442022 @default.
• W2024432944 countsByYear W20244329442023 @default.
• W2024432944 crossrefType "journal-article" @default.
• W2024432944 hasAuthorship W2024432944A5009546678 @default.
• W2024432944 hasAuthorship W2024432944A5011304225 @default.
• W2024432944 hasAuthorship W2024432944A5013548945 @default.
• W2024432944 hasAuthorship W2024432944A5015999389 @default.
• W2024432944 hasAuthorship W2024432944A5017528412 @default.
• W2024432944 hasAuthorship W2024432944A5027160124 @default.
• W2024432944 hasAuthorship W2024432944A5035599848 @default.
• W2024432944 hasAuthorship W2024432944A5045479933 @default.
• W2024432944 hasAuthorship W2024432944A5049031267 @default.
• W2024432944 hasAuthorship W2024432944A5084219685 @default.
• W2024432944 hasBestOaLocation W20244329442 @default.
• W2024432944 hasConcept C119060515 @default.
• W2024432944 hasConcept C126322002 @default.
• W2024432944 hasConcept C142462285 @default.
• W2024432944 hasConcept C167135981 @default.
• W2024432944 hasConcept C187212893 @default.
• W2024432944 hasConcept C194828623 @default.
• W2024432944 hasConcept C195910791 @default.

• next