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• W2024432976 abstract "To examine the role of nitric oxide (NO) in murine AIDS (MAIDS) pathogenesis, we determined NO production and inducible NOS (iNOS) mRNA expression in the macrophages of LP-BM5-infected mice, together with the in vivo effects of l-NAME, a competitive inhibitor of NO synthase. LP-BM5 infection induced neither spontaneous nitrite production nor iNOS mRNA expression. No differences in IFNγ + LPS-induced nitrite production or iNOS mRNA expression were observed in macrophages from non-infected or infected mice. Spleen weight, ecotropic MuLV replication, the blood lymphocyte phenotype and proliferative response of splenocytes were not modified by l-NAME. LP-BM5 infection did not increase macrophage NO production and NO production did not appear to protect against LP-BM5-induced immunodeficiency." @default.
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• W2024432976 date "1996-09-01" @default.
• W2024432976 modified "2023-09-30" @default.
• W2024432976 title "Absence of involvement of nitric oxide in LP-BM5-induced immunodeficiency syndrome" @default.
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• W2024432976 doi "https://doi.org/10.1111/j.1574-695x.1996.tb00068.x" @default.
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