Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024440477> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2024440477 endingPage "129" @default.
- W2024440477 startingPage "121" @default.
- W2024440477 abstract "The nature of both indoor air exposures and noncancer end points present significant issues for risk characterization. Noncancer end points are multidimensional, affecting various organs, and are assumed to have thresholds. Symptoms also vary in severity within a population. In addition to the complexity of noncancer risk assessment, indoor air exposures are typified by the presence of complex mixtures, which further complicates the complex nature of noncancer risk characterization. Most noncancer risk assessment efforts have focused on defining acceptable daily intakes or reference doses (RfD) rather than estimating incidence and severity of the wide range of effects within an exposed population. The risk characterization framework has been developed to accommodate the RfD approach but, more importantly, to address the multidimensional nature of noncancer risk characterization. Newly emerging methods and standard EPA risk assessment guidelines for noncancer effects and complex mixtures were used as guides for developing the framework. Information and data needs have been identified from the framework. Peak, average, and cumulative doses from indoor air exposures are highly dependent on variable indoor air concentrations and affected by time-activity patterns. Susceptibility also plays a significant role in noncancer end points and, unlike susceptibility in cancer risk assessment, is quantifiable. This paper highlights the risk characterization framework for noncancer health risks that we developed in cooperation with the U.S. Environmental Protection Agency Environmental Criteria and Assessment Office. Additionally, a preliminary application of the framework to a complex mixture of volatile organic compounds from indoor sources is illustrated." @default.
- W2024440477 created "2016-06-24" @default.
- W2024440477 creator A5029348777 @default.
- W2024440477 creator A5058835055 @default.
- W2024440477 creator A5064980986 @default.
- W2024440477 date "1991-11-01" @default.
- W2024440477 modified "2023-09-28" @default.
- W2024440477 title "Risk characterization framework for noncancer end points." @default.
- W2024440477 cites W113567586 @default.
- W2024440477 cites W2016139149 @default.
- W2024440477 cites W2024969775 @default.
- W2024440477 cites W2103171961 @default.
- W2024440477 cites W2105646737 @default.
- W2024440477 cites W2132873473 @default.
- W2024440477 cites W2140820151 @default.
- W2024440477 cites W2180000282 @default.
- W2024440477 cites W2320800225 @default.
- W2024440477 doi "https://doi.org/10.1289/ehp.9195121" @default.
- W2024440477 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1568415" @default.
- W2024440477 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1821365" @default.
- W2024440477 hasPublicationYear "1991" @default.
- W2024440477 type Work @default.
- W2024440477 sameAs 2024440477 @default.
- W2024440477 citedByCount "7" @default.
- W2024440477 crossrefType "journal-article" @default.
- W2024440477 hasAuthorship W2024440477A5029348777 @default.
- W2024440477 hasAuthorship W2024440477A5058835055 @default.
- W2024440477 hasAuthorship W2024440477A5064980986 @default.
- W2024440477 hasBestOaLocation W20244404771 @default.
- W2024440477 hasConcept C108170787 @default.
- W2024440477 hasConcept C111472728 @default.
- W2024440477 hasConcept C112930515 @default.
- W2024440477 hasConcept C12174686 @default.
- W2024440477 hasConcept C138885662 @default.
- W2024440477 hasConcept C198408306 @default.
- W2024440477 hasConcept C2908647359 @default.
- W2024440477 hasConcept C38652104 @default.
- W2024440477 hasConcept C41008148 @default.
- W2024440477 hasConcept C71924100 @default.
- W2024440477 hasConcept C99454951 @default.
- W2024440477 hasConceptScore W2024440477C108170787 @default.
- W2024440477 hasConceptScore W2024440477C111472728 @default.
- W2024440477 hasConceptScore W2024440477C112930515 @default.
- W2024440477 hasConceptScore W2024440477C12174686 @default.
- W2024440477 hasConceptScore W2024440477C138885662 @default.
- W2024440477 hasConceptScore W2024440477C198408306 @default.
- W2024440477 hasConceptScore W2024440477C2908647359 @default.
- W2024440477 hasConceptScore W2024440477C38652104 @default.
- W2024440477 hasConceptScore W2024440477C41008148 @default.
- W2024440477 hasConceptScore W2024440477C71924100 @default.
- W2024440477 hasConceptScore W2024440477C99454951 @default.
- W2024440477 hasLocation W20244404771 @default.
- W2024440477 hasLocation W20244404772 @default.
- W2024440477 hasLocation W20244404773 @default.
- W2024440477 hasLocation W20244404774 @default.
- W2024440477 hasOpenAccess W2024440477 @default.
- W2024440477 hasPrimaryLocation W20244404771 @default.
- W2024440477 hasRelatedWork W1901729494 @default.
- W2024440477 hasRelatedWork W2019682640 @default.
- W2024440477 hasRelatedWork W2028222000 @default.
- W2024440477 hasRelatedWork W2038867950 @default.
- W2024440477 hasRelatedWork W2051233639 @default.
- W2024440477 hasRelatedWork W2129926420 @default.
- W2024440477 hasRelatedWork W2392619340 @default.
- W2024440477 hasRelatedWork W2652591151 @default.
- W2024440477 hasRelatedWork W2899084033 @default.
- W2024440477 hasRelatedWork W612100087 @default.
- W2024440477 hasVolume "95" @default.
- W2024440477 isParatext "false" @default.
- W2024440477 isRetracted "false" @default.
- W2024440477 magId "2024440477" @default.
- W2024440477 workType "article" @default.