Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024441018> ?p ?o ?g. }
- W2024441018 endingPage "12228" @default.
- W2024441018 startingPage "12220" @default.
- W2024441018 abstract "The performance of stationary-phase optimized selectivity liquid chromatography (SOS-LC) for improved separation of complex mixtures has been demonstrated before. A dedicated kit containing column segments of different lengths and packed with different stationary phases is commercially available together with algorithms capable of predicting and ranking isocratic and gradient separations over vast amounts of possible column combinations. Implementation in chromatographic separations involving compressible fluids, as is the case in supercritical fluid chromatography, had thus far not been attempted. The challenge of this approach is the dependency of solute retention with the mobile-phase density, complicating linear extrapolation of retention over longer or shorter columns segments, as is the case in conventional SOS-LC. In this study, the possibilities of performing stationary-phase optimized selectivity supercritical fluid chromatography (SOS-SFC) are demonstrated with typical low density mobile phases (94% CO2). The procedure is optimized with the commercially available column kit and with the classical isocratic SOS-LC algorithm. SOS-SFC appears possible without any density correction, although optimal correspondence between prediction and experiment is obtained when isopycnic conditions are maintained. As also the influence of the segment order appears significantly less relevant than expected, the use of the approach in SFC appears as promising as is the case in HPLC. Next to the classical use of SOS for faster baseline separation of all solutes in a mixture, the benefits of the approach for predicting as wide as possible separation windows around to-be-purified solutes in semipreparative SFC are illustrated, leading to significant production rate improvements in (semi)preparative SFC." @default.
- W2024441018 created "2016-06-24" @default.
- W2024441018 creator A5044352603 @default.
- W2024441018 creator A5051369452 @default.
- W2024441018 date "2014-12-01" @default.
- W2024441018 modified "2023-10-04" @default.
- W2024441018 title "Implementing Stationary-Phase Optimized Selectivity in Supercritical Fluid Chromatography" @default.
- W2024441018 cites W108346547 @default.
- W2024441018 cites W122652308 @default.
- W2024441018 cites W1567751864 @default.
- W2024441018 cites W1589420035 @default.
- W2024441018 cites W1815061177 @default.
- W2024441018 cites W1965469047 @default.
- W2024441018 cites W1969393006 @default.
- W2024441018 cites W1969916544 @default.
- W2024441018 cites W1970068910 @default.
- W2024441018 cites W1975294830 @default.
- W2024441018 cites W1975317564 @default.
- W2024441018 cites W1975890572 @default.
- W2024441018 cites W1977493501 @default.
- W2024441018 cites W1988623140 @default.
- W2024441018 cites W1991746363 @default.
- W2024441018 cites W1993740013 @default.
- W2024441018 cites W1998035429 @default.
- W2024441018 cites W1999630925 @default.
- W2024441018 cites W2002780317 @default.
- W2024441018 cites W2008835788 @default.
- W2024441018 cites W2008840494 @default.
- W2024441018 cites W2011659600 @default.
- W2024441018 cites W2016391068 @default.
- W2024441018 cites W2020614974 @default.
- W2024441018 cites W2026705195 @default.
- W2024441018 cites W2026730785 @default.
- W2024441018 cites W2026753112 @default.
- W2024441018 cites W2027651572 @default.
- W2024441018 cites W2028565485 @default.
- W2024441018 cites W2034958523 @default.
- W2024441018 cites W2040917993 @default.
- W2024441018 cites W2048689738 @default.
- W2024441018 cites W2049596715 @default.
- W2024441018 cites W2050597773 @default.
- W2024441018 cites W2052210288 @default.
- W2024441018 cites W2056014133 @default.
- W2024441018 cites W2056189573 @default.
- W2024441018 cites W2058606779 @default.
- W2024441018 cites W2060773420 @default.
- W2024441018 cites W2063975178 @default.
- W2024441018 cites W2064454734 @default.
- W2024441018 cites W2074745508 @default.
- W2024441018 cites W2075619260 @default.
- W2024441018 cites W2076266000 @default.
- W2024441018 cites W2087600316 @default.
- W2024441018 cites W2088045676 @default.
- W2024441018 cites W2089687844 @default.
- W2024441018 cites W2091795678 @default.
- W2024441018 cites W2092285118 @default.
- W2024441018 cites W2092292694 @default.
- W2024441018 cites W2095326002 @default.
- W2024441018 cites W2125840006 @default.
- W2024441018 cites W2135335180 @default.
- W2024441018 cites W2146274920 @default.
- W2024441018 cites W2147409546 @default.
- W2024441018 cites W2184897086 @default.
- W2024441018 cites W2193090403 @default.
- W2024441018 cites W2200305029 @default.
- W2024441018 cites W2211912360 @default.
- W2024441018 cites W2318153681 @default.
- W2024441018 cites W3024610410 @default.
- W2024441018 cites W4251054345 @default.
- W2024441018 cites W83204119 @default.
- W2024441018 cites W905435 @default.
- W2024441018 doi "https://doi.org/10.1021/ac503313j" @default.
- W2024441018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25393519" @default.
- W2024441018 hasPublicationYear "2014" @default.
- W2024441018 type Work @default.
- W2024441018 sameAs 2024441018 @default.
- W2024441018 citedByCount "20" @default.
- W2024441018 countsByYear W20244410182015 @default.
- W2024441018 countsByYear W20244410182016 @default.
- W2024441018 countsByYear W20244410182017 @default.
- W2024441018 countsByYear W20244410182018 @default.
- W2024441018 countsByYear W20244410182019 @default.
- W2024441018 countsByYear W20244410182020 @default.
- W2024441018 countsByYear W20244410182021 @default.
- W2024441018 countsByYear W20244410182022 @default.
- W2024441018 countsByYear W20244410182023 @default.
- W2024441018 crossrefType "journal-article" @default.
- W2024441018 hasAuthorship W2024441018A5044352603 @default.
- W2024441018 hasAuthorship W2024441018A5051369452 @default.
- W2024441018 hasConcept C113196181 @default.
- W2024441018 hasConcept C118419359 @default.
- W2024441018 hasConcept C118792377 @default.
- W2024441018 hasConcept C132459708 @default.
- W2024441018 hasConcept C134306372 @default.
- W2024441018 hasConcept C161790260 @default.
- W2024441018 hasConcept C178790620 @default.
- W2024441018 hasConcept C179998833 @default.
- W2024441018 hasConcept C185592680 @default.