FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024444842> ?p ?o ?g. }

• W2024444842 endingPage "328" @default.
• W2024444842 startingPage "322" @default.
• W2024444842 abstract "The present study investigated the involvement of endothelial nitric oxide in relaxation induced by purified green tea (−)epicatechin in rat isolated mesenteric arteries. (−)Epicatechin caused both endothelium-dependent and -independent relaxation. NG-Nitro-l-arginine methyl ester (l-NAME, 100 μM) and methylene blue (10 μM) significantly attenuated (−)epicatechin-induced relaxation in endothelium-intact tissues. l-Arginine (1 mM) partially antagonized the effect of l-NAME. (−)Epicatechin-induced relaxation was inhibited by Rp-guanosine 3′,5′-cyclic monophosphothioate triethylamine. In contrast, indomethacin and glibenclamide had no effect. (−)Epicatechin (100 μM) significantly increased the tissue content of cyclic GMP and NG-nitro-l-arginine (100 μM) or removal of the endothelium abolished this increase. (−)Epicatechin (100 μM) induced an increase in intracellular Ca2+ levels in cultured human umbilical vein endothelial cells. Iberiotoxin at 100 nM attenuated (−)epicatechin-induced relaxation in endothelium-intact arteries and this effect was absent in the presence of 100 μM l-NAME. In summary, (−)epicatechin-induced endothelium-dependent relaxation is primarily mediated by nitric oxide and partially through nitric oxide-dependent activation of iberiotoxin-sensitive K+ channels. In addition, there may be a causal link between increased Ca2+ levels and nitric oxide release in response to (−)epicatechin." @default.
• W2024444842 created "2016-06-24" @default.
• W2024444842 creator A5001232832 @default.
• W2024444842 creator A5021520609 @default.
• W2024444842 creator A5030534481 @default.
• W2024444842 creator A5034838504 @default.
• W2024444842 creator A5039333280 @default.
• W2024444842 creator A5078350843 @default.
• W2024444842 date "1999-04-19" @default.
• W2024444842 modified "2023-09-27" @default.
• W2024444842 title "Involvement of endothelium/nitric oxide in vasorelaxation induced by purified green tea (−)epicatechin" @default.
• W2024444842 cites W1969639650 @default.
• W2024444842 cites W1971412772 @default.
• W2024444842 cites W1973524109 @default.
• W2024444842 cites W1990845205 @default.
• W2024444842 cites W2003497264 @default.
• W2024444842 cites W2013276694 @default.
• W2024444842 cites W2030967356 @default.
• W2024444842 cites W2041018558 @default.
• W2024444842 cites W2054818418 @default.
• W2024444842 cites W2067423133 @default.
• W2024444842 cites W2067590660 @default.
• W2024444842 cites W2074074731 @default.
• W2024444842 cites W2094797078 @default.
• W2024444842 cites W2106522615 @default.
• W2024444842 cites W2129725829 @default.
• W2024444842 cites W2153100888 @default.
• W2024444842 cites W2157079407 @default.
• W2024444842 cites W2164435773 @default.
• W2024444842 doi "https://doi.org/10.1016/s0304-4165(99)00034-3" @default.
• W2024444842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10216249" @default.
• W2024444842 hasPublicationYear "1999" @default.
• W2024444842 type Work @default.
• W2024444842 sameAs 2024444842 @default.
• W2024444842 citedByCount "88" @default.
• W2024444842 countsByYear W20244448422012 @default.
• W2024444842 countsByYear W20244448422013 @default.
• W2024444842 countsByYear W20244448422014 @default.
• W2024444842 countsByYear W20244448422015 @default.
• W2024444842 countsByYear W20244448422016 @default.
• W2024444842 countsByYear W20244448422017 @default.
• W2024444842 countsByYear W20244448422018 @default.
• W2024444842 countsByYear W20244448422019 @default.
• W2024444842 countsByYear W20244448422020 @default.
• W2024444842 countsByYear W20244448422022 @default.
• W2024444842 countsByYear W20244448422023 @default.
• W2024444842 crossrefType "journal-article" @default.
• W2024444842 hasAuthorship W2024444842A5001232832 @default.
• W2024444842 hasAuthorship W2024444842A5021520609 @default.
• W2024444842 hasAuthorship W2024444842A5030534481 @default.
• W2024444842 hasAuthorship W2024444842A5034838504 @default.
• W2024444842 hasAuthorship W2024444842A5039333280 @default.
• W2024444842 hasAuthorship W2024444842A5078350843 @default.
• W2024444842 hasConcept C12554922 @default.
• W2024444842 hasConcept C126322002 @default.
• W2024444842 hasConcept C134018914 @default.
• W2024444842 hasConcept C161790260 @default.
• W2024444842 hasConcept C178790620 @default.
• W2024444842 hasConcept C185592680 @default.
• W2024444842 hasConcept C202751555 @default.
• W2024444842 hasConcept C2776820930 @default.
• W2024444842 hasConcept C2776992346 @default.
• W2024444842 hasConcept C2777411675 @default.
• W2024444842 hasConcept C2779191827 @default.
• W2024444842 hasConcept C2779411790 @default.
• W2024444842 hasConcept C2779768347 @default.
• W2024444842 hasConcept C2780419564 @default.
• W2024444842 hasConcept C2780733407 @default.
• W2024444842 hasConcept C2780771799 @default.
• W2024444842 hasConcept C517785266 @default.
• W2024444842 hasConcept C519581460 @default.
• W2024444842 hasConcept C55493867 @default.
• W2024444842 hasConcept C555293320 @default.
• W2024444842 hasConcept C65165184 @default.
• W2024444842 hasConcept C71924100 @default.
• W2024444842 hasConcept C86803240 @default.
• W2024444842 hasConcept C98274493 @default.
• W2024444842 hasConceptScore W2024444842C12554922 @default.
• W2024444842 hasConceptScore W2024444842C126322002 @default.
• W2024444842 hasConceptScore W2024444842C134018914 @default.
• W2024444842 hasConceptScore W2024444842C161790260 @default.
• W2024444842 hasConceptScore W2024444842C178790620 @default.
• W2024444842 hasConceptScore W2024444842C185592680 @default.
• W2024444842 hasConceptScore W2024444842C202751555 @default.
• W2024444842 hasConceptScore W2024444842C2776820930 @default.
• W2024444842 hasConceptScore W2024444842C2776992346 @default.
• W2024444842 hasConceptScore W2024444842C2777411675 @default.
• W2024444842 hasConceptScore W2024444842C2779191827 @default.
• W2024444842 hasConceptScore W2024444842C2779411790 @default.
• W2024444842 hasConceptScore W2024444842C2779768347 @default.
• W2024444842 hasConceptScore W2024444842C2780419564 @default.
• W2024444842 hasConceptScore W2024444842C2780733407 @default.
• W2024444842 hasConceptScore W2024444842C2780771799 @default.
• W2024444842 hasConceptScore W2024444842C517785266 @default.
• W2024444842 hasConceptScore W2024444842C519581460 @default.
• W2024444842 hasConceptScore W2024444842C55493867 @default.
• W2024444842 hasConceptScore W2024444842C555293320 @default.
• W2024444842 hasConceptScore W2024444842C65165184 @default.

• next