FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024447227> ?p ?o ?g. }

• W2024447227 endingPage "359" @default.
• W2024447227 startingPage "347" @default.
• W2024447227 abstract "Although isolated chondrocytes can be cryopreserved by standard methods, at the present time there is no satisfactory method that will preserve living chondrocytes in situ in surgical grafts, between the time of procurement or manufacture and actual use; survival of living chondrocytes in situ is inadequate at best and is also very variable. The first step in identifying the cause of this discrepancy was to establish that the cryoprotectants we had chosen to use, dimethyl sulphoxide and propylene glycol, do actually penetrate into the tissue rapidly. They do. Moreover, chondrocytes were shown to tolerate 10 or 20% Me2SO and were not unusually susceptible to osmotic stress. An experiment in which the effects of freezing with 10% Me2SO to -50 degrees C were separated from the effects of the concomitant rise in solute concentration showed that injury was associated with the formation of ice as such. Freeze substitution microscopy showed that large ice crystals were formed within the chondron, some at least within chondrocytes, even when the cooling rate was optimal for isolated chondrocytes. It is proposed that the nucleation and preferential growth of ice within the chondron (rather than the surrounding acellular matrix) is responsible for the very poor survival of chondrocytes in situ when current methods of cartilage cryopreservation are used." @default.
• W2024447227 created "2016-06-24" @default.
• W2024447227 creator A5009365580 @default.
• W2024447227 creator A5027864121 @default.
• W2024447227 creator A5078061801 @default.
• W2024447227 creator A5083469985 @default.
• W2024447227 date "2006-06-01" @default.
• W2024447227 modified "2023-09-25" @default.
• W2024447227 title "Cryopreservation of articular cartilage. Part 2: Mechanisms of cryoinjury" @default.
• W2024447227 cites W1551310212 @default.
• W2024447227 cites W1973211500 @default.
• W2024447227 cites W1973850160 @default.
• W2024447227 cites W1984428412 @default.
• W2024447227 cites W1997636011 @default.
• W2024447227 cites W2000717377 @default.
• W2024447227 cites W2002997248 @default.
• W2024447227 cites W2011915649 @default.
• W2024447227 cites W2026406016 @default.
• W2024447227 cites W2030228662 @default.
• W2024447227 cites W2050087523 @default.
• W2024447227 cites W2071640846 @default.
• W2024447227 cites W2080327315 @default.
• W2024447227 cites W2096123256 @default.
• W2024447227 cites W2125797632 @default.
• W2024447227 cites W2128957639 @default.
• W2024447227 cites W2140314914 @default.
• W2024447227 cites W2159542600 @default.
• W2024447227 cites W2162515752 @default.
• W2024447227 cites W2172216058 @default.
• W2024447227 cites W2259346105 @default.
• W2024447227 cites W2287764834 @default.
• W2024447227 cites W2288980869 @default.
• W2024447227 doi "https://doi.org/10.1016/j.cryobiol.2006.01.007" @default.
• W2024447227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16527262" @default.
• W2024447227 hasPublicationYear "2006" @default.
• W2024447227 type Work @default.
• W2024447227 sameAs 2024447227 @default.
• W2024447227 citedByCount "54" @default.
• W2024447227 countsByYear W20244472272012 @default.
• W2024447227 countsByYear W20244472272013 @default.
• W2024447227 countsByYear W20244472272014 @default.
• W2024447227 countsByYear W20244472272015 @default.
• W2024447227 countsByYear W20244472272016 @default.
• W2024447227 countsByYear W20244472272017 @default.
• W2024447227 countsByYear W20244472272018 @default.
• W2024447227 countsByYear W20244472272019 @default.
• W2024447227 countsByYear W20244472272020 @default.
• W2024447227 countsByYear W20244472272022 @default.
• W2024447227 countsByYear W20244472272023 @default.
• W2024447227 crossrefType "journal-article" @default.
• W2024447227 hasAuthorship W2024447227A5009365580 @default.
• W2024447227 hasAuthorship W2024447227A5027864121 @default.
• W2024447227 hasAuthorship W2024447227A5078061801 @default.
• W2024447227 hasAuthorship W2024447227A5083469985 @default.
• W2024447227 hasConcept C105702510 @default.
• W2024447227 hasConcept C106487976 @default.
• W2024447227 hasConcept C12554922 @default.
• W2024447227 hasConcept C127313418 @default.
• W2024447227 hasConcept C136229726 @default.
• W2024447227 hasConcept C142724271 @default.
• W2024447227 hasConcept C16685009 @default.
• W2024447227 hasConcept C178790620 @default.
• W2024447227 hasConcept C179933525 @default.
• W2024447227 hasConcept C185592680 @default.
• W2024447227 hasConcept C196843134 @default.
• W2024447227 hasConcept C202751555 @default.
• W2024447227 hasConcept C204787440 @default.
• W2024447227 hasConcept C2776164576 @default.
• W2024447227 hasConcept C2778452553 @default.
• W2024447227 hasConcept C2780550940 @default.
• W2024447227 hasConcept C2781403057 @default.
• W2024447227 hasConcept C2992878202 @default.
• W2024447227 hasConcept C3019137385 @default.
• W2024447227 hasConcept C3020332539 @default.
• W2024447227 hasConcept C43617362 @default.
• W2024447227 hasConcept C55493867 @default.
• W2024447227 hasConcept C68528507 @default.
• W2024447227 hasConcept C71924100 @default.
• W2024447227 hasConcept C86803240 @default.
• W2024447227 hasConcept C91586092 @default.
• W2024447227 hasConcept C95053279 @default.
• W2024447227 hasConcept C95444343 @default.
• W2024447227 hasConceptScore W2024447227C105702510 @default.
• W2024447227 hasConceptScore W2024447227C106487976 @default.
• W2024447227 hasConceptScore W2024447227C12554922 @default.
• W2024447227 hasConceptScore W2024447227C127313418 @default.
• W2024447227 hasConceptScore W2024447227C136229726 @default.
• W2024447227 hasConceptScore W2024447227C142724271 @default.
• W2024447227 hasConceptScore W2024447227C16685009 @default.
• W2024447227 hasConceptScore W2024447227C178790620 @default.
• W2024447227 hasConceptScore W2024447227C179933525 @default.
• W2024447227 hasConceptScore W2024447227C185592680 @default.
• W2024447227 hasConceptScore W2024447227C196843134 @default.
• W2024447227 hasConceptScore W2024447227C202751555 @default.
• W2024447227 hasConceptScore W2024447227C204787440 @default.
• W2024447227 hasConceptScore W2024447227C2776164576 @default.
• W2024447227 hasConceptScore W2024447227C2778452553 @default.
• W2024447227 hasConceptScore W2024447227C2780550940 @default.

• next