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- W2024448766 abstract "In Reply.— There is no best way to ascertain clinically which solitary cold thyroid nodule is malignant. Mature judgment will lead to one or a combination of diagnostic tools. Our publication assessed prospectively the value in predicting cancer of the two following approaches that are commonly used and about which there are little hard data: (1) factors derived from the history and physical examination that are immediately available to the average primary physician without a consultant, and (2) the response to three months of suppressive therapy. Three fourths of our cancers came from the high-risk group, and in these patients neither suppressive therapy nor needle biopsy was needed to make an accurate diagnosis. Since 50% of this group had carcinoma and 30% adenoma, it is clear from our results that when there are high-risk factors a negative needle biopsy result should not deter surgery. The majority of the patients, those" @default.
- W2024448766 created "2016-06-24" @default.
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- W2024448766 date "1980-12-05" @default.
- W2024448766 modified "2023-09-27" @default.
- W2024448766 title "The Solitary Thyroid Nodule-Reply" @default.
- W2024448766 cites W2048742976 @default.
- W2024448766 doi "https://doi.org/10.1001/jama.1980.03310220021011" @default.
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