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- W2024451508 abstract "The effects of hypothalamic electrical stimulation and dl-sulpiride injections on the unit activity of masticatory trigeminal neurons were assessed in rats. Unilateral electrodes or bilateral cannulas were implanted in the perifornical hypothalamus. The animals which exhibited eating to electrical stimulation or to sulpiride injections were selected. Then, under urethane anesthesia, electrical stimuli or sulpiride injections were applied at sites which elicited eating while a passive jaw movement-related neuron was recorded. Electrical stimulation or sulpiride injections affected the basal firing rate of 15 out of 32 (53%), and 13 out of 17 (76%) jaw movement-related neurons, respectively. The basal firing rate of 3 out of 18 (16.6%) was affected by electrical stimulation of noneliciting feeding nearby places. Facilitation was observed in 7 out of those 13 jaw movement-related trigeminal neurons after intrahypothalamic sulpiride injections. When dopamine was injected in the hypothalamus 3 minutes before sulpiride, this drug could only affect the basal firing rate of 1 out of 12 (8%) jaw movement-related neurons. The electrical stimulation and sulpiride injections into the hypothalamus had the same inhibitory or excitatory effect on a given trigeminal neuron as the passive jaw movement did. A similar phenomenon was observed with the sulpiride-induced facilitation. These results suggest that hypothalamic D2 satiety receptors modulate brain stem feeding reflexes." @default.
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- W2024451508 date "1991-03-01" @default.
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- W2024451508 title "Hypothalamic sites affecting masticatory neurons in rats" @default.
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- W2024451508 doi "https://doi.org/10.1016/0361-9230(91)90001-z" @default.
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