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- W2024454436 abstract "The in vitro activity of liver microsomal enzymes to metabolize some aromatic and chlorinated hydrocarbons was enhanced remarkably in 1-day fasted rats of both sexes, although fasting produced no significant increase in the microsomal protein and cytochrome P-450 contents. Even the activity per whole liver was at a significantly increased level, despite the fact that fasting caused a marked loss of liver weight. A sex difference was noted in the metabolism of these hydrocarbons both in fed and 1-day fasted rats. However, food deprivation for 3 days was found to decrease the extent of this sex difference. A metabolism study using trichloroethylene as a model substrate showed that the rate of metabolism in vivo was also enhanced by fasting." @default.
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- W2024454436 title "Enhanced activity of liver drug-metabolizing enzymes for aromatic and chlorinated hydrocarbons following food deprivation" @default.
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- W2024454436 doi "https://doi.org/10.1016/0041-008x(79)90409-5" @default.
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