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• W2024455076 abstract "In this Letter we describe the design, synthesis, screening, and optimization of a new family of ADAMTS-5 inhibitors. These inhibitors display an original 1,2,4-triazole-3-thiol scaffold as a putative zinc binding-group. In vitro results are rationalized by in silico docking of the compounds in ADAMTS-5’s crystal structure." @default.
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• W2024455076 date "2010-11-01" @default.
• W2024455076 modified "2023-10-13" @default.
• W2024455076 title "New non-hydroxamic ADAMTS-5 inhibitors based on the 1,2,4-triazole-3-thiol scaffold" @default.
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• W2024455076 doi "https://doi.org/10.1016/j.bmcl.2010.08.108" @default.
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