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- W2024455571 abstract "at 1800mg QW. No DLT has been observed so far in the QW regimen up to 1800mg. Sustained disease stabilization has been observed mainly in soft tissue sarcoma patients. An expansion cohort was opened for the QD schedule, with 21 pts with dedifferentiated liposarcoma treated at 300mg QD. Conclusions: p53 pathway activation and adequate safety in patients have been demonstrated with SAR405838, which supports the ongoing evaluation in monotherapy and combination therapies. The study is sponsored by Sanofi Oncology; NCT01636479." @default.
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- W2024455571 date "2014-11-01" @default.
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- W2024455571 title "379 Identification and rational in silico-based targeting of a novel mediator of metastatic breast cancer" @default.
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