Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024459158> ?p ?o ?g. }
- W2024459158 endingPage "561" @default.
- W2024459158 startingPage "549" @default.
- W2024459158 abstract "Human chorionic gonadotropin (hCG) is mainly used for detection and monitoring of pregnancy and pregnancy-related disorders but it is also an extremely sensitive and specific marker for trophoblastic tumors of placental and germ cell origin. Thus treatment of relapsing choriocarcinomas and testicular germ cell tumors is often initiated on the basis of rising hCG levels even in the absence of clinical or histological evidence of a relapse. While these tumors mostly produce the intact heterodimeric hormone consisting of an α (hCGα), and a β subunit (hCGβ), many nontrophoblastic tumors produce only hCGβ This is usually a sign of aggressive disease and elevated serum levels of hCGβ are strongly associated with poor prognosis. Elevated serum levels are observed in 45–60% of patients with biliary and pancreatic cancer and in 10–30% of most other cancers. Methods that detect hCG and hCGβ together are mainly used for measurement of hCG-like immunoreactivity in serum. However, the reference range for hCG is 5–8 fold higher than that for hCGβ and thus moderately elevated levels can be identified only with a specific and sensitive hCGβ assay." @default.
- W2024459158 created "2016-06-24" @default.
- W2024459158 creator A5005660879 @default.
- W2024459158 creator A5046649062 @default.
- W2024459158 creator A5051002496 @default.
- W2024459158 date "2004-07-01" @default.
- W2024459158 modified "2023-10-16" @default.
- W2024459158 title "Human chorionic gonadotropin in cancer" @default.
- W2024459158 cites W1513725699 @default.
- W2024459158 cites W153810884 @default.
- W2024459158 cites W157283203 @default.
- W2024459158 cites W1610439870 @default.
- W2024459158 cites W1814660981 @default.
- W2024459158 cites W1824055483 @default.
- W2024459158 cites W1859530484 @default.
- W2024459158 cites W1895001325 @default.
- W2024459158 cites W1903066579 @default.
- W2024459158 cites W191374670 @default.
- W2024459158 cites W1916998316 @default.
- W2024459158 cites W1926822185 @default.
- W2024459158 cites W1953926689 @default.
- W2024459158 cites W1964100434 @default.
- W2024459158 cites W1965773879 @default.
- W2024459158 cites W1965817514 @default.
- W2024459158 cites W1965878844 @default.
- W2024459158 cites W1967430398 @default.
- W2024459158 cites W1972355395 @default.
- W2024459158 cites W1973064760 @default.
- W2024459158 cites W1973708077 @default.
- W2024459158 cites W1973859002 @default.
- W2024459158 cites W1974710518 @default.
- W2024459158 cites W1975550550 @default.
- W2024459158 cites W1977759039 @default.
- W2024459158 cites W1977985341 @default.
- W2024459158 cites W1978973179 @default.
- W2024459158 cites W1979474323 @default.
- W2024459158 cites W1979978234 @default.
- W2024459158 cites W1983230977 @default.
- W2024459158 cites W1983595431 @default.
- W2024459158 cites W1984285971 @default.
- W2024459158 cites W1992647935 @default.
- W2024459158 cites W1992899654 @default.
- W2024459158 cites W1993001306 @default.
- W2024459158 cites W1998851121 @default.
- W2024459158 cites W1999039650 @default.
- W2024459158 cites W2000166392 @default.
- W2024459158 cites W2000168107 @default.
- W2024459158 cites W2004343332 @default.
- W2024459158 cites W2007657295 @default.
- W2024459158 cites W2009125028 @default.
- W2024459158 cites W2013173247 @default.
- W2024459158 cites W2013804324 @default.
- W2024459158 cites W2014623046 @default.
- W2024459158 cites W2017951498 @default.
- W2024459158 cites W2019089889 @default.
- W2024459158 cites W2019610134 @default.
- W2024459158 cites W2020959256 @default.
- W2024459158 cites W2021285765 @default.
- W2024459158 cites W2023344651 @default.
- W2024459158 cites W2027264438 @default.
- W2024459158 cites W2030715776 @default.
- W2024459158 cites W2031192188 @default.
- W2024459158 cites W2034576960 @default.
- W2024459158 cites W2037407466 @default.
- W2024459158 cites W2037641864 @default.
- W2024459158 cites W2042026283 @default.
- W2024459158 cites W2042960001 @default.
- W2024459158 cites W2051209173 @default.
- W2024459158 cites W2051645114 @default.
- W2024459158 cites W2053141742 @default.
- W2024459158 cites W2053800335 @default.
- W2024459158 cites W2054403141 @default.
- W2024459158 cites W2055842383 @default.
- W2024459158 cites W2056495338 @default.
- W2024459158 cites W2057784873 @default.
- W2024459158 cites W2059337136 @default.
- W2024459158 cites W2059769136 @default.
- W2024459158 cites W2061653183 @default.
- W2024459158 cites W2061993034 @default.
- W2024459158 cites W2062106765 @default.
- W2024459158 cites W2064403751 @default.
- W2024459158 cites W2065663430 @default.
- W2024459158 cites W2065811361 @default.
- W2024459158 cites W2066956204 @default.
- W2024459158 cites W2068045682 @default.
- W2024459158 cites W2068225770 @default.
- W2024459158 cites W2069245875 @default.
- W2024459158 cites W2070411860 @default.
- W2024459158 cites W2070587260 @default.
- W2024459158 cites W2070678781 @default.
- W2024459158 cites W2074405172 @default.
- W2024459158 cites W2075371108 @default.
- W2024459158 cites W2079726591 @default.
- W2024459158 cites W2083996252 @default.
- W2024459158 cites W2084441219 @default.
- W2024459158 cites W2085495056 @default.
- W2024459158 cites W2086523638 @default.
- W2024459158 cites W2087072361 @default.