FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024467994> ?p ?o ?g. }

• W2024467994 endingPage "1330" @default.
• W2024467994 startingPage "1316" @default.
• W2024467994 abstract "Microarray experiments have yielded massive amounts of expression information measured under various conditions for the model species Arabidopsis (Arabidopsis thaliana) and rice (Oryza sativa). Expression compendia grouping multiple experiments make it possible to define correlated gene expression patterns within one species and to study how expression has evolved between species. We developed a robust framework to measure expression context conservation (ECC) and found, by analyzing 4,630 pairs of orthologous Arabidopsis and rice genes, that 77% showed conserved coexpression. Examples of nonconserved ECC categories suggested a link between regulatory evolution and environmental adaptations and included genes involved in signal transduction, response to different abiotic stresses, and hormone stimuli. To identify genomic features that influence expression evolution, we analyzed the relationship between ECC, tissue specificity, and protein evolution. Tissue-specific genes showed higher expression conservation compared with broadly expressed genes but were fast evolving at the protein level. No significant correlation was found between protein and expression evolution, implying that both modes of gene evolution are not strongly coupled in plants. By integration of cis-regulatory elements, many ECC conserved genes were significantly enriched for shared DNA motifs, hinting at the conservation of ancestral regulatory interactions in both model species. Surprisingly, for several tissue-specific genes, patterns of concerted network evolution were observed, unveiling conserved coexpression in the absence of conservation of tissue specificity. These findings demonstrate that orthologs inferred through sequence similarity in many cases do not share similar biological functions and highlight the importance of incorporating expression information when comparing genes across species." @default.
• W2024467994 created "2016-06-24" @default.
• W2024467994 creator A5018330202 @default.
• W2024467994 creator A5052680833 @default.
• W2024467994 creator A5070738091 @default.
• W2024467994 date "2011-05-13" @default.
• W2024467994 modified "2023-10-16" @default.
• W2024467994 title "Comparative Network Analysis Reveals That Tissue Specificity and Gene Function Are Important Factors Influencing the Mode of Expression Evolution in Arabidopsis and Rice " @default.
• W2024467994 cites W1702565916 @default.
• W2024467994 cites W1970871693 @default.
• W2024467994 cites W1986376668 @default.
• W2024467994 cites W1986662234 @default.
• W2024467994 cites W1999828066 @default.
• W2024467994 cites W2000004737 @default.
• W2024467994 cites W2000297641 @default.
• W2024467994 cites W2000408270 @default.
• W2024467994 cites W2000495354 @default.
• W2024467994 cites W2010535008 @default.
• W2024467994 cites W2029617325 @default.
• W2024467994 cites W2030909328 @default.
• W2024467994 cites W2040308159 @default.
• W2024467994 cites W2045534443 @default.
• W2024467994 cites W2048009853 @default.
• W2024467994 cites W2048682154 @default.
• W2024467994 cites W2049046860 @default.
• W2024467994 cites W2053427298 @default.
• W2024467994 cites W2060012074 @default.
• W2024467994 cites W2065172786 @default.
• W2024467994 cites W2069102911 @default.
• W2024467994 cites W2069420439 @default.
• W2024467994 cites W2070647407 @default.
• W2024467994 cites W2079808772 @default.
• W2024467994 cites W2082990265 @default.
• W2024467994 cites W2099601400 @default.
• W2024467994 cites W2100945610 @default.
• W2024467994 cites W2104567831 @default.
• W2024467994 cites W2106074168 @default.
• W2024467994 cites W2115111790 @default.
• W2024467994 cites W2116255719 @default.
• W2024467994 cites W2117023724 @default.
• W2024467994 cites W2117543773 @default.
• W2024467994 cites W2120965285 @default.
• W2024467994 cites W2125508747 @default.
• W2024467994 cites W2126623160 @default.
• W2024467994 cites W2129243798 @default.
• W2024467994 cites W2130353827 @default.
• W2024467994 cites W2134744211 @default.
• W2024467994 cites W2135119668 @default.
• W2024467994 cites W2135160221 @default.
• W2024467994 cites W2135861471 @default.
• W2024467994 cites W2136749660 @default.
• W2024467994 cites W2142055410 @default.
• W2024467994 cites W2143335572 @default.
• W2024467994 cites W2148498486 @default.
• W2024467994 cites W2150926065 @default.
• W2024467994 cites W2151233592 @default.
• W2024467994 cites W2151404319 @default.
• W2024467994 cites W2151638049 @default.
• W2024467994 cites W2152379610 @default.
• W2024467994 cites W2155651473 @default.
• W2024467994 cites W2156970791 @default.
• W2024467994 cites W2158287613 @default.
• W2024467994 cites W2159049360 @default.
• W2024467994 cites W2159699532 @default.
• W2024467994 cites W2162142896 @default.
• W2024467994 cites W2165247488 @default.
• W2024467994 cites W2166033346 @default.
• W2024467994 cites W2170824309 @default.
• W2024467994 cites W2170989872 @default.
• W2024467994 cites W4229799243 @default.
• W2024467994 doi "https://doi.org/10.1104/pp.111.177865" @default.
• W2024467994 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3135928" @default.
• W2024467994 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21571672" @default.
• W2024467994 hasPublicationYear "2011" @default.
• W2024467994 type Work @default.
• W2024467994 sameAs 2024467994 @default.
• W2024467994 citedByCount "98" @default.
• W2024467994 countsByYear W20244679942012 @default.
• W2024467994 countsByYear W20244679942013 @default.
• W2024467994 countsByYear W20244679942014 @default.
• W2024467994 countsByYear W20244679942015 @default.
• W2024467994 countsByYear W20244679942016 @default.
• W2024467994 countsByYear W20244679942017 @default.
• W2024467994 countsByYear W20244679942018 @default.
• W2024467994 countsByYear W20244679942019 @default.
• W2024467994 countsByYear W20244679942020 @default.
• W2024467994 countsByYear W20244679942021 @default.
• W2024467994 countsByYear W20244679942022 @default.
• W2024467994 countsByYear W20244679942023 @default.
• W2024467994 crossrefType "journal-article" @default.
• W2024467994 hasAuthorship W2024467994A5018330202 @default.
• W2024467994 hasAuthorship W2024467994A5052680833 @default.
• W2024467994 hasAuthorship W2024467994A5070738091 @default.
• W2024467994 hasBestOaLocation W20244679941 @default.
• W2024467994 hasConcept C104317684 @default.
• W2024467994 hasConcept C143065580 @default.
• W2024467994 hasConcept C150194340 @default.
• W2024467994 hasConcept C151730666 @default.

• next