Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024486539> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2024486539 endingPage "128" @default.
- W2024486539 startingPage "123" @default.
- W2024486539 abstract "A key step towards understanding the development and function of the central nervous system is by characterizing the connections between neurons. Tetanus toxin C fragment (TTC) is transynaptically and retrogradely transported without the toxin's pathogenic effect, and therefore, recently it has been used as a genetic tracer combined with beta-galactosidase or green fluorescent protein. Here, we introduce a new fusion construct, APTTC, consisting of the truncated human placental alkaline phosphatase with TTC, and generating the transgenic mouse line, (tetracycline operator) tetO-APTTC, for inducible expression of APTTC regulated by tetO. We demonstrate that APTTC is transported retrogradely and transynaptically, and allows us to robustly visualize the inputs of the expressing neurons when transgenetically expressed in mice, exemplified in the striatal neuronal circuit. Therefore, tetO-APTTC transgenic mouse line can be widely used for visualization of neuronal connectivity when combined with mice carrying tetracycline-controlled transactivator (tTA) in any specific neurons." @default.
- W2024486539 created "2016-06-24" @default.
- W2024486539 creator A5006632335 @default.
- W2024486539 creator A5040279911 @default.
- W2024486539 creator A5070814001 @default.
- W2024486539 date "2007-01-01" @default.
- W2024486539 modified "2023-10-15" @default.
- W2024486539 title "Inducible expression of retrograde transynaptic genetic tracer in mice" @default.
- W2024486539 cites W1498646052 @default.
- W2024486539 cites W1538926863 @default.
- W2024486539 cites W1935461641 @default.
- W2024486539 cites W1975997959 @default.
- W2024486539 cites W1980419833 @default.
- W2024486539 cites W2011029903 @default.
- W2024486539 cites W2013631479 @default.
- W2024486539 cites W2040603263 @default.
- W2024486539 cites W2054693278 @default.
- W2024486539 cites W2060122782 @default.
- W2024486539 cites W2060893463 @default.
- W2024486539 cites W2064442671 @default.
- W2024486539 cites W2065635189 @default.
- W2024486539 cites W2069186336 @default.
- W2024486539 cites W2076163730 @default.
- W2024486539 cites W2079589334 @default.
- W2024486539 cites W2090429649 @default.
- W2024486539 cites W2122977798 @default.
- W2024486539 cites W2126148882 @default.
- W2024486539 cites W3023504226 @default.
- W2024486539 doi "https://doi.org/10.1002/dvg.20273" @default.
- W2024486539 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17299748" @default.
- W2024486539 hasPublicationYear "2007" @default.
- W2024486539 type Work @default.
- W2024486539 sameAs 2024486539 @default.
- W2024486539 citedByCount "9" @default.
- W2024486539 countsByYear W20244865392018 @default.
- W2024486539 countsByYear W20244865392020 @default.
- W2024486539 crossrefType "journal-article" @default.
- W2024486539 hasAuthorship W2024486539A5006632335 @default.
- W2024486539 hasAuthorship W2024486539A5040279911 @default.
- W2024486539 hasAuthorship W2024486539A5070814001 @default.
- W2024486539 hasConcept C102230213 @default.
- W2024486539 hasConcept C104317684 @default.
- W2024486539 hasConcept C1292079 @default.
- W2024486539 hasConcept C141035611 @default.
- W2024486539 hasConcept C142613039 @default.
- W2024486539 hasConcept C150194340 @default.
- W2024486539 hasConcept C153911025 @default.
- W2024486539 hasConcept C169760540 @default.
- W2024486539 hasConcept C54355233 @default.
- W2024486539 hasConcept C86803240 @default.
- W2024486539 hasConcept C95444343 @default.
- W2024486539 hasConceptScore W2024486539C102230213 @default.
- W2024486539 hasConceptScore W2024486539C104317684 @default.
- W2024486539 hasConceptScore W2024486539C1292079 @default.
- W2024486539 hasConceptScore W2024486539C141035611 @default.
- W2024486539 hasConceptScore W2024486539C142613039 @default.
- W2024486539 hasConceptScore W2024486539C150194340 @default.
- W2024486539 hasConceptScore W2024486539C153911025 @default.
- W2024486539 hasConceptScore W2024486539C169760540 @default.
- W2024486539 hasConceptScore W2024486539C54355233 @default.
- W2024486539 hasConceptScore W2024486539C86803240 @default.
- W2024486539 hasConceptScore W2024486539C95444343 @default.
- W2024486539 hasIssue "3" @default.
- W2024486539 hasLocation W20244865391 @default.
- W2024486539 hasLocation W20244865392 @default.
- W2024486539 hasOpenAccess W2024486539 @default.
- W2024486539 hasPrimaryLocation W20244865391 @default.
- W2024486539 hasRelatedWork W1536426327 @default.
- W2024486539 hasRelatedWork W1973459962 @default.
- W2024486539 hasRelatedWork W2030084515 @default.
- W2024486539 hasRelatedWork W2064668712 @default.
- W2024486539 hasRelatedWork W2070974215 @default.
- W2024486539 hasRelatedWork W2109840577 @default.
- W2024486539 hasRelatedWork W2113540885 @default.
- W2024486539 hasRelatedWork W2158124286 @default.
- W2024486539 hasRelatedWork W2398991683 @default.
- W2024486539 hasRelatedWork W2407241705 @default.
- W2024486539 hasVolume "45" @default.
- W2024486539 isParatext "false" @default.
- W2024486539 isRetracted "false" @default.
- W2024486539 magId "2024486539" @default.
- W2024486539 workType "article" @default.