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• W2024489056 abstract "A series of conjugates of peptide nucleic acids (PNA) and Zr(IV) complexes was prepared. Their ability to hydrolyze DNA was tested using MALDI-TOF mass spectrometry and HPLC. The most efficient artificial restriction enzyme found, PNA conjugate with Zr(IV) complex of tris(hydroxymethyl)-aminomethane, cleaves DNA targets sequence selectively in close proximity to the Zr(IV) complex. It was demonstrated that cleavage products are substrates of terminal transferase." @default.
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• W2024489056 date "2003-11-20" @default.
• W2024489056 modified "2023-10-02" @default.
• W2024489056 title "Sequence Selective Hydrolysis of Linear DNA Using Conjugates of Zr(IV) Complexes and Peptide Nucleic Acids" @default.
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• W2024489056 doi "https://doi.org/10.1021/ic034896v" @default.
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