Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024502785> ?p ?o ?g. }
- W2024502785 endingPage "586" @default.
- W2024502785 startingPage "577" @default.
- W2024502785 abstract "Although steady-state methadone (SSM) treatment is mainly used for opioid addiction, some clinical studies indicate that it also reduces cocaine abuse in opioid-dependent individuals.To present evidence suggesting that SSM may be useful in the treatment of cocaine addiction without pre-existing opioid dependence. We review studies in animals investigating the effects of SSM on behaviors motivated by cocaine and on cocaine-induced alterations of genes expression in the rat brain.SSM reduces cocaine intake, blocks cocaine seeking and normalizes expression of genes known to regulate cocaine seeking. These findings suggest that SSM could be an effective pharmacological agent to assist cocaine detoxification and prevention of relapse to cocaine abuse in individuals not co-dependent on opioid." @default.
- W2024502785 created "2016-06-24" @default.
- W2024502785 creator A5032968625 @default.
- W2024502785 creator A5057354424 @default.
- W2024502785 date "2009-05-01" @default.
- W2024502785 modified "2023-09-24" @default.
- W2024502785 title "Animal studies trigger new insights on the use of methadone maintenance" @default.
- W2024502785 cites W1561258900 @default.
- W2024502785 cites W1574751342 @default.
- W2024502785 cites W1782902465 @default.
- W2024502785 cites W1950553701 @default.
- W2024502785 cites W1964710304 @default.
- W2024502785 cites W1965048571 @default.
- W2024502785 cites W1967566314 @default.
- W2024502785 cites W1967642433 @default.
- W2024502785 cites W1969779239 @default.
- W2024502785 cites W1970655997 @default.
- W2024502785 cites W1971389354 @default.
- W2024502785 cites W1972505350 @default.
- W2024502785 cites W1974567127 @default.
- W2024502785 cites W1976722832 @default.
- W2024502785 cites W1979097034 @default.
- W2024502785 cites W1979204332 @default.
- W2024502785 cites W1983112762 @default.
- W2024502785 cites W1983332126 @default.
- W2024502785 cites W1983399730 @default.
- W2024502785 cites W1985100821 @default.
- W2024502785 cites W1985115851 @default.
- W2024502785 cites W1988950772 @default.
- W2024502785 cites W1993145481 @default.
- W2024502785 cites W1993453206 @default.
- W2024502785 cites W1995455950 @default.
- W2024502785 cites W1996515732 @default.
- W2024502785 cites W1997597637 @default.
- W2024502785 cites W1998425896 @default.
- W2024502785 cites W1999948756 @default.
- W2024502785 cites W2002518106 @default.
- W2024502785 cites W2006030101 @default.
- W2024502785 cites W2011083127 @default.
- W2024502785 cites W2011235590 @default.
- W2024502785 cites W2012584862 @default.
- W2024502785 cites W2013608634 @default.
- W2024502785 cites W2013851440 @default.
- W2024502785 cites W2013924762 @default.
- W2024502785 cites W2014786760 @default.
- W2024502785 cites W2015296096 @default.
- W2024502785 cites W2019466708 @default.
- W2024502785 cites W2020245525 @default.
- W2024502785 cites W2023475082 @default.
- W2024502785 cites W2024799504 @default.
- W2024502785 cites W2026509713 @default.
- W2024502785 cites W2027740042 @default.
- W2024502785 cites W2029351727 @default.
- W2024502785 cites W2029419162 @default.
- W2024502785 cites W2031402825 @default.
- W2024502785 cites W2036442617 @default.
- W2024502785 cites W2038127945 @default.
- W2024502785 cites W2040903782 @default.
- W2024502785 cites W2041018266 @default.
- W2024502785 cites W2041405553 @default.
- W2024502785 cites W2044676961 @default.
- W2024502785 cites W2044746762 @default.
- W2024502785 cites W2045927851 @default.
- W2024502785 cites W2049796382 @default.
- W2024502785 cites W2051625171 @default.
- W2024502785 cites W2054825229 @default.
- W2024502785 cites W2055462210 @default.
- W2024502785 cites W2056018109 @default.
- W2024502785 cites W2057344593 @default.
- W2024502785 cites W2058213757 @default.
- W2024502785 cites W2059414185 @default.
- W2024502785 cites W2060173097 @default.
- W2024502785 cites W2061515123 @default.
- W2024502785 cites W2065816932 @default.
- W2024502785 cites W2066044316 @default.
- W2024502785 cites W2067915574 @default.
- W2024502785 cites W2068735847 @default.
- W2024502785 cites W2069642322 @default.
- W2024502785 cites W2069726169 @default.
- W2024502785 cites W2071098488 @default.
- W2024502785 cites W2071497507 @default.
- W2024502785 cites W2071540538 @default.
- W2024502785 cites W2072255226 @default.
- W2024502785 cites W2072671458 @default.
- W2024502785 cites W2075750309 @default.
- W2024502785 cites W2076016967 @default.
- W2024502785 cites W2076941707 @default.
- W2024502785 cites W2079427523 @default.
- W2024502785 cites W2079853768 @default.
- W2024502785 cites W2081812523 @default.
- W2024502785 cites W2081875838 @default.
- W2024502785 cites W2082671861 @default.
- W2024502785 cites W2083035314 @default.
- W2024502785 cites W2088550924 @default.
- W2024502785 cites W2088979113 @default.
- W2024502785 cites W2094149815 @default.
- W2024502785 cites W2094957254 @default.
- W2024502785 cites W2095595575 @default.