Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024503990> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2024503990 endingPage "986" @default.
- W2024503990 startingPage "983" @default.
- W2024503990 abstract "In view of the potency-enhancing effect of methyl substitution of the piperidine ring of the 4-phenylpiperidine analgesics and (he alkylene chain of the acyclic basic anilide analgesics, the 1-methyl, 1-benzyl, and 1-phenylethyl derivatives of 2-methyl-, 3-methyl-, and 2,5-dimethyl-4-propananilidopiperidine were prepared. The analgesic activity of these compounds indicates that 3- methylation has the greatest effect in enhancing analgesjc potency whereas 2-methyl and 2,5-dimethyl substitution is detrimental to analgesic activity. In view of the potency-enhancing effect of methyl substitution of the piperidine ring of the 4-phenylpiperidine analgesics and (he alkylene chain of the acyclic basic anilide analgesics, the 1-methyl, 1-benzyl, and 1-phenylethyl derivatives of 2-methyl-, 3-methyl-, and 2,5-dimethyl-4-propananilidopiperidine were prepared. The analgesic activity of these compounds indicates that 3- methylation has the greatest effect in enhancing analgesjc potency whereas 2-methyl and 2,5-dimethyl substitution is detrimental to analgesic activity." @default.
- W2024503990 created "2016-06-24" @default.
- W2024503990 creator A5035351200 @default.
- W2024503990 creator A5063913447 @default.
- W2024503990 creator A5069634105 @default.
- W2024503990 date "1973-06-01" @default.
- W2024503990 modified "2023-09-26" @default.
- W2024503990 title "4-Anilidopiperidine Analgesics I: Synthesis and Analgesic Activity of Certain Ring-Methylated 1-Substituted 4-Propananilidopiperidines" @default.
- W2024503990 cites W1963617320 @default.
- W2024503990 cites W1984197333 @default.
- W2024503990 cites W2022586601 @default.
- W2024503990 cites W2036200603 @default.
- W2024503990 cites W2132344933 @default.
- W2024503990 cites W2173051616 @default.
- W2024503990 cites W2408995423 @default.
- W2024503990 doi "https://doi.org/10.1002/jps.2600620627" @default.
- W2024503990 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4712637" @default.
- W2024503990 hasPublicationYear "1973" @default.
- W2024503990 type Work @default.
- W2024503990 sameAs 2024503990 @default.
- W2024503990 citedByCount "33" @default.
- W2024503990 countsByYear W20245039902012 @default.
- W2024503990 countsByYear W20245039902014 @default.
- W2024503990 countsByYear W20245039902015 @default.
- W2024503990 countsByYear W20245039902017 @default.
- W2024503990 countsByYear W20245039902018 @default.
- W2024503990 crossrefType "journal-article" @default.
- W2024503990 hasAuthorship W2024503990A5035351200 @default.
- W2024503990 hasAuthorship W2024503990A5063913447 @default.
- W2024503990 hasAuthorship W2024503990A5069634105 @default.
- W2024503990 hasConcept C155647269 @default.
- W2024503990 hasConcept C178790620 @default.
- W2024503990 hasConcept C185592680 @default.
- W2024503990 hasConcept C202751555 @default.
- W2024503990 hasConcept C2780378348 @default.
- W2024503990 hasConcept C2780820201 @default.
- W2024503990 hasConcept C2781462491 @default.
- W2024503990 hasConcept C33288867 @default.
- W2024503990 hasConcept C552990157 @default.
- W2024503990 hasConcept C55493867 @default.
- W2024503990 hasConcept C57992300 @default.
- W2024503990 hasConcept C71240020 @default.
- W2024503990 hasConcept C71924100 @default.
- W2024503990 hasConcept C98274493 @default.
- W2024503990 hasConceptScore W2024503990C155647269 @default.
- W2024503990 hasConceptScore W2024503990C178790620 @default.
- W2024503990 hasConceptScore W2024503990C185592680 @default.
- W2024503990 hasConceptScore W2024503990C202751555 @default.
- W2024503990 hasConceptScore W2024503990C2780378348 @default.
- W2024503990 hasConceptScore W2024503990C2780820201 @default.
- W2024503990 hasConceptScore W2024503990C2781462491 @default.
- W2024503990 hasConceptScore W2024503990C33288867 @default.
- W2024503990 hasConceptScore W2024503990C552990157 @default.
- W2024503990 hasConceptScore W2024503990C55493867 @default.
- W2024503990 hasConceptScore W2024503990C57992300 @default.
- W2024503990 hasConceptScore W2024503990C71240020 @default.
- W2024503990 hasConceptScore W2024503990C71924100 @default.
- W2024503990 hasConceptScore W2024503990C98274493 @default.
- W2024503990 hasIssue "6" @default.
- W2024503990 hasLocation W20245039901 @default.
- W2024503990 hasLocation W20245039902 @default.
- W2024503990 hasOpenAccess W2024503990 @default.
- W2024503990 hasPrimaryLocation W20245039901 @default.
- W2024503990 hasRelatedWork W1841680247 @default.
- W2024503990 hasRelatedWork W2004760842 @default.
- W2024503990 hasRelatedWork W2024503990 @default.
- W2024503990 hasRelatedWork W2040920850 @default.
- W2024503990 hasRelatedWork W2058677416 @default.
- W2024503990 hasRelatedWork W2086068589 @default.
- W2024503990 hasRelatedWork W2399541805 @default.
- W2024503990 hasRelatedWork W2413943946 @default.
- W2024503990 hasRelatedWork W3149759195 @default.
- W2024503990 hasRelatedWork W4246276609 @default.
- W2024503990 hasVolume "62" @default.
- W2024503990 isParatext "false" @default.
- W2024503990 isRetracted "false" @default.
- W2024503990 magId "2024503990" @default.
- W2024503990 workType "article" @default.