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- W2024505508 abstract "The link between oncogenesis and normal development is well illustrated by the study of the Wnt family of proteins. The first Wnt gene (int-1) was identified over a decade ago as a proto-oncogene, activated in response to proviral insertion of a mouse mammary tumor virus. Subsequently, the discovery that Drosophila wingless, a developmentally important gene, is homologous to int-1 supported the notion that int-1 may have a role in normal development. In the last few years it has been recognized that int-1 and Wingless belong to a large family of related glyco-proteins found in vertebrates and invertebrates. In recognition of this, members of this family have been renamed Wnts, an amalgam of int and Wingless. Investigation of Wnt genes in Xenopus and mouse indicates that Wnts have a role in cell proliferation, differentiation and body axis formation. Further analysis in Drosophila has revealed that Wingless function is required in several developmental processes in the embryo and imaginal discs. In addition, a genetic approach has identified some of the molecules required for the transmission and reception of the Wingless signal. We will review recent data which have contributed to our growing understanding of the function and mechanism of Drosophila Wingless signaling in cell fate determination, growth and specification of pattern." @default.
- W2024505508 created "2016-06-24" @default.
- W2024505508 creator A5049978049 @default.
- W2024505508 creator A5071083794 @default.
- W2024505508 date "1994-06-01" @default.
- W2024505508 modified "2023-10-04" @default.
- W2024505508 title "Drosophila wingless: A paradigm for the function and mechanism of Wnt signaling" @default.
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- W2024505508 cites W15778579 @default.
- W2024505508 cites W1819149160 @default.
- W2024505508 cites W1819307633 @default.
- W2024505508 cites W1867994916 @default.
- W2024505508 cites W1878064618 @default.
- W2024505508 cites W1889389895 @default.
- W2024505508 cites W1889767892 @default.
- W2024505508 cites W1911201077 @default.
- W2024505508 cites W194137483 @default.
- W2024505508 cites W1964545876 @default.
- W2024505508 cites W1970759130 @default.
- W2024505508 cites W1971767351 @default.
- W2024505508 cites W1972727772 @default.
- W2024505508 cites W1979040385 @default.
- W2024505508 cites W1980238084 @default.
- W2024505508 cites W1980878261 @default.
- W2024505508 cites W1981778651 @default.
- W2024505508 cites W1984713273 @default.
- W2024505508 cites W1987918178 @default.
- W2024505508 cites W1989194294 @default.
- W2024505508 cites W1989721036 @default.
- W2024505508 cites W1991461487 @default.
- W2024505508 cites W1992465003 @default.
- W2024505508 cites W2008815241 @default.
- W2024505508 cites W2010044764 @default.
- W2024505508 cites W2013548303 @default.
- W2024505508 cites W2015100891 @default.
- W2024505508 cites W2020773645 @default.
- W2024505508 cites W2021210221 @default.
- W2024505508 cites W2024435992 @default.
- W2024505508 cites W2025682939 @default.
- W2024505508 cites W2026377725 @default.
- W2024505508 cites W2027304196 @default.
- W2024505508 cites W2030491643 @default.
- W2024505508 cites W2031880491 @default.
- W2024505508 cites W2033291406 @default.
- W2024505508 cites W2033513529 @default.
- W2024505508 cites W2033618020 @default.
- W2024505508 cites W2035140381 @default.
- W2024505508 cites W2037697367 @default.
- W2024505508 cites W2041498658 @default.
- W2024505508 cites W2046804699 @default.
- W2024505508 cites W2048924533 @default.
- W2024505508 cites W2049829724 @default.
- W2024505508 cites W2050763240 @default.
- W2024505508 cites W2054184290 @default.
- W2024505508 cites W2062655106 @default.
- W2024505508 cites W2062682308 @default.
- W2024505508 cites W2062890130 @default.
- W2024505508 cites W2070566380 @default.
- W2024505508 cites W2071915231 @default.
- W2024505508 cites W2073304650 @default.
- W2024505508 cites W2080363826 @default.
- W2024505508 cites W2081689397 @default.
- W2024505508 cites W2084377907 @default.
- W2024505508 cites W2084771679 @default.
- W2024505508 cites W2085730270 @default.
- W2024505508 cites W2089545402 @default.
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- W2024505508 cites W2104000274 @default.
- W2024505508 cites W2109744312 @default.
- W2024505508 cites W2123769327 @default.
- W2024505508 cites W2154987409 @default.
- W2024505508 cites W2157934217 @default.
- W2024505508 cites W2160777888 @default.
- W2024505508 cites W2164418509 @default.
- W2024505508 cites W2165781463 @default.
- W2024505508 cites W2169478707 @default.
- W2024505508 cites W2219499873 @default.
- W2024505508 cites W2224822722 @default.
- W2024505508 cites W2294833613 @default.
- W2024505508 cites W2412108038 @default.
- W2024505508 cites W2422481370 @default.
- W2024505508 cites W2472955934 @default.
- W2024505508 cites W4211089574 @default.
- W2024505508 cites W4240072047 @default.
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- W2024505508 doi "https://doi.org/10.1002/bies.950160607" @default.
- W2024505508 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8080429" @default.
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