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- W2024509945 abstract "Little is known about the central projection patterns of trigeminal afferent neurons expressing the vanilloid receptor TRPV1 and their coexpression of neuromodulatory peptides. To address these issues, we examined the distribution of TRPV1-positive neurons in the trigeminal ganglion (TG) and trigeminal sensory nuclei principalis (Vp), oralis (Vo), interpolaris (Vi), and caudalis (Vc) in the rat via light and electron microscopy. In addition, we studied the colocalization of TRPV1-positive neurons with substance P (SP) and calcitonin gene-related peptide (CGRP) via confocal microscopy. In TG, only small and medium-sized neurons were immunopositive for TRPV1. The staining for TRPV1 was found in axon collaterals in the dorsal parts of Vp, Vo, and Vi and in terminals and fibers throughout lamina I and the outer zone of lamina II (IIo) of Vc. With electron microscopy, TRPV1-positive fibers in the ascending and descending trigeminal tracts were found to be unmyelinated. Almost all TRPV1-positive terminals in Vc contained numerous large dense-core vesicles and formed synaptic contacts with single small dendrites. Multiple immunofluorescence revealed a high degree of colocalization of TRPV1 with SP and CGRP in TG neurons as well as in fibers and terminals confined to laminae I and IIo of Vc. These results suggest that the central projections of unmyelinated (C) afferents sensitive to noxious heat and capsaicin are organized differently between Vc and the rostral trigeminal nuclei and that Vc may play a role in the development of hyperalgesia. J. Comp. Neurol. 478:62–71, 2004. © 2004 Wiley-Liss, Inc." @default.
- W2024509945 created "2016-06-24" @default.
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- W2024509945 date "2004-01-01" @default.
- W2024509945 modified "2023-10-16" @default.
- W2024509945 title "Expression of vanilloid receptor TRPV1 in the rat trigeminal sensory nuclei" @default.
- W2024509945 cites W120308028 @default.
- W2024509945 cites W1495409864 @default.
- W2024509945 cites W1505180943 @default.
- W2024509945 cites W1511198581 @default.
- W2024509945 cites W1832611062 @default.
- W2024509945 cites W1871284454 @default.
- W2024509945 cites W1908231918 @default.
- W2024509945 cites W1928547908 @default.
- W2024509945 cites W1968280298 @default.
- W2024509945 cites W1969065510 @default.
- W2024509945 cites W1970405412 @default.
- W2024509945 cites W1972421997 @default.
- W2024509945 cites W1974932149 @default.
- W2024509945 cites W1978290569 @default.
- W2024509945 cites W1982714604 @default.
- W2024509945 cites W1989273149 @default.
- W2024509945 cites W1996281763 @default.
- W2024509945 cites W1998196415 @default.
- W2024509945 cites W2000062290 @default.
- W2024509945 cites W2002158618 @default.
- W2024509945 cites W2003404396 @default.
- W2024509945 cites W2005796755 @default.
- W2024509945 cites W2007400067 @default.
- W2024509945 cites W2009855911 @default.
- W2024509945 cites W2020588358 @default.
- W2024509945 cites W2021534866 @default.
- W2024509945 cites W2022356687 @default.
- W2024509945 cites W2027957851 @default.
- W2024509945 cites W2029015778 @default.
- W2024509945 cites W2029130327 @default.
- W2024509945 cites W2029445814 @default.
- W2024509945 cites W2032831616 @default.
- W2024509945 cites W2033064989 @default.
- W2024509945 cites W2034572815 @default.
- W2024509945 cites W2035385809 @default.
- W2024509945 cites W2037048763 @default.
- W2024509945 cites W2037099123 @default.
- W2024509945 cites W2038024944 @default.
- W2024509945 cites W2042772701 @default.
- W2024509945 cites W2045742729 @default.
- W2024509945 cites W2047385100 @default.
- W2024509945 cites W2048188839 @default.
- W2024509945 cites W2050781058 @default.
- W2024509945 cites W2050987374 @default.
- W2024509945 cites W2054583723 @default.
- W2024509945 cites W2057812251 @default.
- W2024509945 cites W2067759963 @default.
- W2024509945 cites W2069404682 @default.
- W2024509945 cites W2071881010 @default.
- W2024509945 cites W2084647104 @default.
- W2024509945 cites W2085052553 @default.
- W2024509945 cites W2086765385 @default.
- W2024509945 cites W2089308945 @default.
- W2024509945 cites W2090472806 @default.
- W2024509945 cites W2107705149 @default.
- W2024509945 cites W2109293109 @default.
- W2024509945 cites W2109317340 @default.
- W2024509945 cites W2110551626 @default.
- W2024509945 cites W2133113968 @default.
- W2024509945 cites W2136099176 @default.
- W2024509945 cites W2143634900 @default.
- W2024509945 cites W2147082948 @default.
- W2024509945 cites W2171809335 @default.
- W2024509945 cites W2221889561 @default.
- W2024509945 cites W2253176756 @default.
- W2024509945 cites W2329157933 @default.
- W2024509945 cites W2346891312 @default.
- W2024509945 cites W2403091635 @default.
- W2024509945 cites W2404958010 @default.
- W2024509945 cites W2405019314 @default.
- W2024509945 cites W2417092171 @default.
- W2024509945 doi "https://doi.org/10.1002/cne.20272" @default.
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- W2024509945 hasPublicationYear "2004" @default.
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