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- W2024528265 abstract "The galactose-mediated clearance of serum glycoproteins from the circulation was evaluated using beta-1,4-galactosyltransferase (beta-1,4-GalT) I-knockout mice. Partial structural study of the oligosaccharides released from mouse serum glycoproteins revealed that 77.4% of the oligosaccharides from beta-1,4-GalT I(+/+) mouse contain galactose, while 7.7% of those from beta-1,4-GalT I(-/-) mouse were galactosylated. Under the conditions, no significant change in serum protein concentrations was observed between the normal and mutant mice. The results indicate that the hepatic asialoglycoprotein receptor-mediated system is not functioning in the clearance of endogenous serum glycoproteins." @default.
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- W2024528265 date "1999-12-20" @default.
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- W2024528265 title "Normal levels of serum glycoproteins maintained in β-1,4-galactosyltransferase I-knockout mice" @default.
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- W2024528265 doi "https://doi.org/10.1016/s0014-5793(99)01681-6" @default.
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