FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024531728> ?p ?o ?g. }

• W2024531728 endingPage "94" @default.
• W2024531728 startingPage "89" @default.
• W2024531728 abstract "In the present study, we examined a role of mitogen-activated protein kinases (MAPKs), extracellular signal-related kinase (ERK), c-Jun N-terminal protein kinase, and p38 MAPK in troglitazone-induced inhibition of cell growth in human pancreatic cancer cells. Among the three kinases, troglitazone specifically inhibited the phosphorylation of ERK1/2 in a dose- and time-dependent manner. Troglitazone also down-regulated the protein expression of mitogen-activated protein kinase kinase (MEK)1/2, an upstream molecule that regulates ERK phosphorylation. Treatment of human pancreatic cancer cells with specific MEK inhibitor, PD98059 or U0126, inhibited ERK1/2 phosphorylation and cell growth. These results suggest for the first time that the inhibition of the MEK1/2–ERK1/2 signaling pathway may be implicated in the growth inhibitory effect by troglitazone in human pancreatic cancer cells." @default.
• W2024531728 created "2016-06-24" @default.
• W2024531728 creator A5012679101 @default.
• W2024531728 creator A5013878244 @default.
• W2024531728 creator A5042942861 @default.
• W2024531728 creator A5054072947 @default.
• W2024531728 creator A5067861714 @default.
• W2024531728 creator A5069703142 @default.
• W2024531728 creator A5076990413 @default.
• W2024531728 date "2005-06-01" @default.
• W2024531728 modified "2023-10-16" @default.
• W2024531728 title "Involvement of MEK–ERK signaling pathway in the inhibition of cell growth by troglitazone in human pancreatic cancer cells" @default.
• W2024531728 cites W1494491432 @default.
• W2024531728 cites W1566737177 @default.
• W2024531728 cites W1944726467 @default.
• W2024531728 cites W1966861485 @default.
• W2024531728 cites W1969294711 @default.
• W2024531728 cites W1971271340 @default.
• W2024531728 cites W1971915141 @default.
• W2024531728 cites W1974063618 @default.
• W2024531728 cites W1975160900 @default.
• W2024531728 cites W1976257037 @default.
• W2024531728 cites W1993342645 @default.
• W2024531728 cites W1994212260 @default.
• W2024531728 cites W1996413533 @default.
• W2024531728 cites W1996647025 @default.
• W2024531728 cites W2000235958 @default.
• W2024531728 cites W2031216738 @default.
• W2024531728 cites W2031694725 @default.
• W2024531728 cites W2047591801 @default.
• W2024531728 cites W2056625507 @default.
• W2024531728 cites W2063888227 @default.
• W2024531728 cites W2078818685 @default.
• W2024531728 cites W2086262311 @default.
• W2024531728 cites W2091124516 @default.
• W2024531728 cites W2091321756 @default.
• W2024531728 cites W2092104789 @default.
• W2024531728 cites W2127150495 @default.
• W2024531728 cites W2150557496 @default.
• W2024531728 cites W2171518012 @default.
• W2024531728 cites W2172256092 @default.
• W2024531728 doi "https://doi.org/10.1016/j.bbrc.2005.04.095" @default.
• W2024531728 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15896303" @default.
• W2024531728 hasPublicationYear "2005" @default.
• W2024531728 type Work @default.
• W2024531728 sameAs 2024531728 @default.
• W2024531728 citedByCount "39" @default.
• W2024531728 countsByYear W20245317282012 @default.
• W2024531728 countsByYear W20245317282013 @default.
• W2024531728 countsByYear W20245317282014 @default.
• W2024531728 countsByYear W20245317282015 @default.
• W2024531728 countsByYear W20245317282016 @default.
• W2024531728 countsByYear W20245317282017 @default.
• W2024531728 countsByYear W20245317282018 @default.
• W2024531728 countsByYear W20245317282020 @default.
• W2024531728 countsByYear W20245317282021 @default.
• W2024531728 countsByYear W20245317282022 @default.
• W2024531728 countsByYear W20245317282023 @default.
• W2024531728 crossrefType "journal-article" @default.
• W2024531728 hasAuthorship W2024531728A5012679101 @default.
• W2024531728 hasAuthorship W2024531728A5013878244 @default.
• W2024531728 hasAuthorship W2024531728A5042942861 @default.
• W2024531728 hasAuthorship W2024531728A5054072947 @default.
• W2024531728 hasAuthorship W2024531728A5067861714 @default.
• W2024531728 hasAuthorship W2024531728A5069703142 @default.
• W2024531728 hasAuthorship W2024531728A5076990413 @default.
• W2024531728 hasBestOaLocation W20245317282 @default.
• W2024531728 hasConcept C11960822 @default.
• W2024531728 hasConcept C121608353 @default.
• W2024531728 hasConcept C126322002 @default.
• W2024531728 hasConcept C132149769 @default.
• W2024531728 hasConcept C170493617 @default.
• W2024531728 hasConcept C184235292 @default.
• W2024531728 hasConcept C185592680 @default.
• W2024531728 hasConcept C187345961 @default.
• W2024531728 hasConcept C2778150266 @default.
• W2024531728 hasConcept C2780210213 @default.
• W2024531728 hasConcept C2781249067 @default.
• W2024531728 hasConcept C502942594 @default.
• W2024531728 hasConcept C51551487 @default.
• W2024531728 hasConcept C55493867 @default.
• W2024531728 hasConcept C57074206 @default.
• W2024531728 hasConcept C71924100 @default.
• W2024531728 hasConcept C86803240 @default.
• W2024531728 hasConcept C90934575 @default.
• W2024531728 hasConcept C95444343 @default.
• W2024531728 hasConcept C97029542 @default.
• W2024531728 hasConceptScore W2024531728C11960822 @default.
• W2024531728 hasConceptScore W2024531728C121608353 @default.
• W2024531728 hasConceptScore W2024531728C126322002 @default.
• W2024531728 hasConceptScore W2024531728C132149769 @default.
• W2024531728 hasConceptScore W2024531728C170493617 @default.
• W2024531728 hasConceptScore W2024531728C184235292 @default.
• W2024531728 hasConceptScore W2024531728C185592680 @default.
• W2024531728 hasConceptScore W2024531728C187345961 @default.
• W2024531728 hasConceptScore W2024531728C2778150266 @default.
• W2024531728 hasConceptScore W2024531728C2780210213 @default.
• W2024531728 hasConceptScore W2024531728C2781249067 @default.

• next