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• W2024531880 abstract "Positive-strand RNA [(+)RNA] viruses are responsible for numerous human, animal, and plant diseases. Because of the limiting coding capacity of (+)RNA viruses, their replication requires a complex orchestration of interactions between the viral genome, viral proteins and exploited host factors. To replicate their genomic RNAs, (+)RNA viruses induce membrane rearrangements that create membrane-linked RNA replication compartments. Along with substantial advances on the ultrastructure of the membrane-bound RNA replication compartments, recent results have shed light into the role that host factors play in rearranging these membranes. This review focuses on recent insights that have driven a new understanding of the role that the membrane-shaping host reticulon homology domain proteins (RHPs) play in facilitating the replication of various (+)RNA viruses." @default.
• W2024531880 created "2016-06-24" @default.
• W2024531880 creator A5026899432 @default.
• W2024531880 creator A5070022149 @default.
• W2024531880 date "2012-08-01" @default.
• W2024531880 modified "2023-10-13" @default.
• W2024531880 title "Role of host reticulon proteins in rearranging membranes for positive-strand RNA virus replication" @default.
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• W2024531880 doi "https://doi.org/10.1016/j.mib.2012.04.007" @default.
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