FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024542987> ?p ?o ?g. }

• W2024542987 endingPage "H2513" @default.
• W2024542987 startingPage "H2508" @default.
• W2024542987 abstract "Because adenosine is commonly used for inducing maximal coronary hyperemia in the clinic, it is imperative that adenosine-induced hyperemia (AH) resembles coronary hyperemia that can be attained by endogenous stimuli. In the present study we hypothesized that coronary reactive hyperemia (RH) is limited compared with AH due to the presence of the glycocalyx and that the AH response is therefore unable to detect glycocalyx modifications. In anesthetized open-chest dogs, blood flow and pressure were measured in the left circumflex artery. RH after 15-s occlusion was compared with an intracoronary infusion of adenosine (650 μg; AH) during control conditions and after intracoronary treatment of the glycocalyx with hyaluronidase (20.000 U, 2 × 20 min; n = 6) or heat-inactivated hyaluronidase ( n = 5). During control, coronary conductance during RH was 1.49 ± 0.15 ml·mmHg −1 ·min −1 and 76 ± 7% of coronary conductance during AH ( P < 0.05). After hyaluronidase, RH conductance increased ( P < 0.01) by 43 ± 13% and became 93 ± 4% of AH conductance ( P = NS). Heat-inactivated hyaluronidase had no effect on RH and AH conductance. Our results demonstrate that adenosine-induced coronary hyperemia profoundly exceeds RH and that the difference is virtually abolished on selective removal of the glycocalyx. It is concluded that, compared with RH, adenosine-induced coronary hyperemia is not affected by modification of the glycocalyx. This glycocalyx insensitivity should be taken into account when using adenosine-induced coronary hyperemia as a marker for vasodilating capacity to an ischemic stimulus." @default.
• W2024542987 created "2016-06-24" @default.
• W2024542987 creator A5006347548 @default.
• W2024542987 creator A5013695013 @default.
• W2024542987 creator A5020636730 @default.
• W2024542987 creator A5029300724 @default.
• W2024542987 creator A5081430387 @default.
• W2024542987 creator A5089369359 @default.
• W2024542987 date "2005-12-01" @default.
• W2024542987 modified "2023-10-17" @default.
• W2024542987 title "Hyaluronidase treatment of coronary glycocalyx increases reactive hyperemia but not adenosine hyperemia in dog hearts" @default.
• W2024542987 cites W1599476364 @default.
• W2024542987 cites W1966104018 @default.
• W2024542987 cites W1968291833 @default.
• W2024542987 cites W1971912931 @default.
• W2024542987 cites W1973773296 @default.
• W2024542987 cites W1976276573 @default.
• W2024542987 cites W2041527418 @default.
• W2024542987 cites W2058172582 @default.
• W2024542987 cites W2058936197 @default.
• W2024542987 cites W2088443855 @default.
• W2024542987 cites W2098274894 @default.
• W2024542987 cites W2099991755 @default.
• W2024542987 cites W2101773230 @default.
• W2024542987 cites W2107661763 @default.
• W2024542987 cites W2133930237 @default.
• W2024542987 cites W2145164028 @default.
• W2024542987 cites W2151788304 @default.
• W2024542987 cites W2152543475 @default.
• W2024542987 cites W2153035007 @default.
• W2024542987 cites W2155099369 @default.
• W2024542987 cites W2156156866 @default.
• W2024542987 cites W2157028830 @default.
• W2024542987 cites W2161982204 @default.
• W2024542987 cites W2162551249 @default.
• W2024542987 cites W2166943958 @default.
• W2024542987 cites W2168489155 @default.
• W2024542987 cites W2180631886 @default.
• W2024542987 cites W2236490931 @default.
• W2024542987 cites W2264734041 @default.
• W2024542987 cites W2409610347 @default.
• W2024542987 cites W4239351357 @default.
• W2024542987 cites W75166960 @default.
• W2024542987 cites W177424105 @default.
• W2024542987 doi "https://doi.org/10.1152/ajpheart.00446.2005" @default.
• W2024542987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16040715" @default.
• W2024542987 hasPublicationYear "2005" @default.
• W2024542987 type Work @default.
• W2024542987 sameAs 2024542987 @default.
• W2024542987 citedByCount "26" @default.
• W2024542987 countsByYear W20245429872012 @default.
• W2024542987 countsByYear W20245429872013 @default.
• W2024542987 countsByYear W20245429872014 @default.
• W2024542987 countsByYear W20245429872016 @default.
• W2024542987 countsByYear W20245429872017 @default.
• W2024542987 countsByYear W20245429872020 @default.
• W2024542987 countsByYear W20245429872021 @default.
• W2024542987 crossrefType "journal-article" @default.
• W2024542987 hasAuthorship W2024542987A5006347548 @default.
• W2024542987 hasAuthorship W2024542987A5013695013 @default.
• W2024542987 hasAuthorship W2024542987A5020636730 @default.
• W2024542987 hasAuthorship W2024542987A5029300724 @default.
• W2024542987 hasAuthorship W2024542987A5081430387 @default.
• W2024542987 hasAuthorship W2024542987A5089369359 @default.
• W2024542987 hasConcept C120770815 @default.
• W2024542987 hasConcept C126322002 @default.
• W2024542987 hasConcept C164705383 @default.
• W2024542987 hasConcept C181199279 @default.
• W2024542987 hasConcept C185592680 @default.
• W2024542987 hasConcept C203014093 @default.
• W2024542987 hasConcept C2776268601 @default.
• W2024542987 hasConcept C2776991684 @default.
• W2024542987 hasConcept C2780098789 @default.
• W2024542987 hasConcept C2780375986 @default.
• W2024542987 hasConcept C2780393670 @default.
• W2024542987 hasConcept C3019128504 @default.
• W2024542987 hasConcept C42219234 @default.
• W2024542987 hasConcept C55493867 @default.
• W2024542987 hasConcept C71924100 @default.
• W2024542987 hasConceptScore W2024542987C120770815 @default.
• W2024542987 hasConceptScore W2024542987C126322002 @default.
• W2024542987 hasConceptScore W2024542987C164705383 @default.
• W2024542987 hasConceptScore W2024542987C181199279 @default.
• W2024542987 hasConceptScore W2024542987C185592680 @default.
• W2024542987 hasConceptScore W2024542987C203014093 @default.
• W2024542987 hasConceptScore W2024542987C2776268601 @default.
• W2024542987 hasConceptScore W2024542987C2776991684 @default.
• W2024542987 hasConceptScore W2024542987C2780098789 @default.
• W2024542987 hasConceptScore W2024542987C2780375986 @default.
• W2024542987 hasConceptScore W2024542987C2780393670 @default.
• W2024542987 hasConceptScore W2024542987C3019128504 @default.
• W2024542987 hasConceptScore W2024542987C42219234 @default.
• W2024542987 hasConceptScore W2024542987C55493867 @default.
• W2024542987 hasConceptScore W2024542987C71924100 @default.
• W2024542987 hasIssue "6" @default.
• W2024542987 hasLocation W20245429871 @default.
• W2024542987 hasLocation W20245429872 @default.
• W2024542987 hasOpenAccess W2024542987 @default.

• next