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- W2024543841 abstract "Academic Press, 1993. £77.00 hbk (463 pages) ISBN 0 12 429350 65 Signal Transduction: Prokaryotic and Simple Eukaryotzc Systems illustrates the common nature of the signaling mechanisms in two distinct groups of organisms, prokaryotes and lower eukaryotes. One LS struck by a recu,ring theme involving the response of a cell-surface receptor protein to a chemical or physical stimulus: the receptor changes its association with an mtracellular effector protein, imtiating an amplification cascade that culminates in a change of behavior or gene expresston. As this book attests, it is becoming clear that the parachgms used by 'simple organisms' are often similar, and sometimes tdentical, to those found in mammals, However, molecular-genetic manipulations are generally easier in simpler systems, and are also especially amenable to biochemical analysis. Therefore, fundamental principles of signal transduction have been, and will continue to be, derived from studies in prokaryotes and lower eukaryotes. Four chapters of this book are devoted to prokaryotic systems, Considering the many important contributions that have emerged from studies of these organisms, the editors faced a difficult task In deciding the scope of these chapters. The first two focus on eubacterlal chemotaxls, perhaps the best-understood signal transductton pathway" @default.
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- W2024543841 date "1994-10-01" @default.
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- W2024543841 title "Signal transduction: Prokaryotic and simple eukaryotic systems" @default.
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- W2024543841 doi "https://doi.org/10.1016/0168-9525(94)90136-8" @default.
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