Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024549946> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2024549946 endingPage "757" @default.
- W2024549946 startingPage "750" @default.
- W2024549946 abstract "Seventeen organophosphate, three carbamate and one sulfamate compounds were topically applied to female house flies (Musca domestica (L.)) to determine the correlation between toxicity, symptomology and in vivo inhibition of brain cholinesterase activity. The surviving flies from an LD50 dose of all the compounds went through hyperactive and paralytic symptoms and definite brain cholinesterase inhibition before recovery. Except for the carbamate, Isolan, the brain cholinesterase recovered completely with 1280 minutes and with several compounds the recovery was complete 80 minutes after treatment. The time of the highest rate of mortality in the insecticide-treated population and of paralytic symptoms in the survivors was usually closely associated with the time of maximum enzyme inhibition. Marathon was the major exception where the greatest paralysis and mortality occurred after the cholinesterase activity had shown considerable recovery. By assaying the brain cholinesterase at varying substrate concentrations it was found that at the stage of hyperactivity and early paralysis in poisoning a shift occurred in the optimum substrate concentration. This might be due to a transitory competitive stage in the cholinesterase inhibition with certain organophosphates prior to phosphorylation of the enzyme and the dephosphorylation involved in recovery. Alternative explanations are also considered." @default.
- W2024549946 created "2016-06-24" @default.
- W2024549946 creator A5042386496 @default.
- W2024549946 creator A5048493992 @default.
- W2024549946 date "1958-12-01" @default.
- W2024549946 modified "2023-09-27" @default.
- W2024549946 title "Inhibition and Recovery of Brain Cholinesterase Activity in House Flies Poisoned with Organophosphate and Carbamate Compounds1" @default.
- W2024549946 doi "https://doi.org/10.1093/jee/51.6.750" @default.
- W2024549946 hasPublicationYear "1958" @default.
- W2024549946 type Work @default.
- W2024549946 sameAs 2024549946 @default.
- W2024549946 citedByCount "33" @default.
- W2024549946 countsByYear W20245499462013 @default.
- W2024549946 countsByYear W20245499462018 @default.
- W2024549946 countsByYear W20245499462021 @default.
- W2024549946 countsByYear W20245499462022 @default.
- W2024549946 crossrefType "journal-article" @default.
- W2024549946 hasAuthorship W2024549946A5042386496 @default.
- W2024549946 hasAuthorship W2024549946A5048493992 @default.
- W2024549946 hasConcept C141071460 @default.
- W2024549946 hasConcept C161176658 @default.
- W2024549946 hasConcept C178666793 @default.
- W2024549946 hasConcept C181199279 @default.
- W2024549946 hasConcept C181912034 @default.
- W2024549946 hasConcept C18903297 @default.
- W2024549946 hasConcept C2775910092 @default.
- W2024549946 hasConcept C2776588719 @default.
- W2024549946 hasConcept C2776663719 @default.
- W2024549946 hasConcept C2779303437 @default.
- W2024549946 hasConcept C2779618896 @default.
- W2024549946 hasConcept C2908647359 @default.
- W2024549946 hasConcept C31896038 @default.
- W2024549946 hasConcept C33070731 @default.
- W2024549946 hasConcept C55493867 @default.
- W2024549946 hasConcept C71924100 @default.
- W2024549946 hasConcept C86803240 @default.
- W2024549946 hasConcept C98274493 @default.
- W2024549946 hasConcept C99454951 @default.
- W2024549946 hasConceptScore W2024549946C141071460 @default.
- W2024549946 hasConceptScore W2024549946C161176658 @default.
- W2024549946 hasConceptScore W2024549946C178666793 @default.
- W2024549946 hasConceptScore W2024549946C181199279 @default.
- W2024549946 hasConceptScore W2024549946C181912034 @default.
- W2024549946 hasConceptScore W2024549946C18903297 @default.
- W2024549946 hasConceptScore W2024549946C2775910092 @default.
- W2024549946 hasConceptScore W2024549946C2776588719 @default.
- W2024549946 hasConceptScore W2024549946C2776663719 @default.
- W2024549946 hasConceptScore W2024549946C2779303437 @default.
- W2024549946 hasConceptScore W2024549946C2779618896 @default.
- W2024549946 hasConceptScore W2024549946C2908647359 @default.
- W2024549946 hasConceptScore W2024549946C31896038 @default.
- W2024549946 hasConceptScore W2024549946C33070731 @default.
- W2024549946 hasConceptScore W2024549946C55493867 @default.
- W2024549946 hasConceptScore W2024549946C71924100 @default.
- W2024549946 hasConceptScore W2024549946C86803240 @default.
- W2024549946 hasConceptScore W2024549946C98274493 @default.
- W2024549946 hasConceptScore W2024549946C99454951 @default.
- W2024549946 hasIssue "6" @default.
- W2024549946 hasLocation W20245499461 @default.
- W2024549946 hasOpenAccess W2024549946 @default.
- W2024549946 hasPrimaryLocation W20245499461 @default.
- W2024549946 hasRelatedWork W1008243866 @default.
- W2024549946 hasRelatedWork W1501118700 @default.
- W2024549946 hasRelatedWork W1970098396 @default.
- W2024549946 hasRelatedWork W2019520258 @default.
- W2024549946 hasRelatedWork W2024549946 @default.
- W2024549946 hasRelatedWork W2064876803 @default.
- W2024549946 hasRelatedWork W2067469664 @default.
- W2024549946 hasRelatedWork W2111568366 @default.
- W2024549946 hasRelatedWork W2372893884 @default.
- W2024549946 hasRelatedWork W2399328668 @default.
- W2024549946 hasVolume "51" @default.
- W2024549946 isParatext "false" @default.
- W2024549946 isRetracted "false" @default.
- W2024549946 magId "2024549946" @default.
- W2024549946 workType "article" @default.