Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024556554> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2024556554 abstract "The application of gold nanoparticles as a contrast agent in optical bioimaging is well appreciated, but limited to a narrow excitation range due to its rather invariable optical resonance typically at 520 nm. Compared to gold nanoparticles, the optical response of gold nanoshells can be tuned to match the higher excitation wavelength of many promising clinical reflectance-based imaging modalities such as the optical coherence tomography (OCT). In this study, we demonstrate the tunability of gold nanoshells to improve the optical contrast of backscattering signal under confocal reflectance microscopy and OCT. The gold nanoshells were synthesized and conjugated to antibodies for in vitro demonstration of their selective optical contrast in cancer cells over normal cells under the confocal reflectance microscopy. The OCT signals from these gold nanoshells were compared to that from bare silica cores and intrinsic tissue scattering using 1% Intralipid. We have shown that gold nanoshells are able to elicit an optical contrast to discriminate between cancerous and normal cells under the confocal reflectance microscopy based on differences in molecular markers expression. Compared to bare silica core, the presence of the gold shell is able to effect a higher backscattered OCT signal with an apparent contrast over 1% Intralipid. This contrast can be made to be dependent on the molecular marker expression with antibody specificity." @default.
- W2024556554 created "2016-06-24" @default.
- W2024556554 creator A5020348826 @default.
- W2024556554 creator A5027637490 @default.
- W2024556554 creator A5038492659 @default.
- W2024556554 creator A5047000678 @default.
- W2024556554 creator A5074116993 @default.
- W2024556554 creator A5090064925 @default.
- W2024556554 date "2007-07-05" @default.
- W2024556554 modified "2023-09-26" @default.
- W2024556554 title "Improving the optical contrast of backscattering signal in reflectance-based imaging with gold nanoshells" @default.
- W2024556554 cites W1853499144 @default.
- W2024556554 cites W1991786174 @default.
- W2024556554 cites W2018192364 @default.
- W2024556554 cites W2021247836 @default.
- W2024556554 cites W2021996848 @default.
- W2024556554 cites W2024665366 @default.
- W2024556554 cites W2033433582 @default.
- W2024556554 cites W2043009832 @default.
- W2024556554 cites W2046350457 @default.
- W2024556554 cites W2071224672 @default.
- W2024556554 cites W2080376276 @default.
- W2024556554 cites W2102947851 @default.
- W2024556554 cites W2108873458 @default.
- W2024556554 cites W2137335948 @default.
- W2024556554 cites W2155329472 @default.
- W2024556554 cites W2162034088 @default.
- W2024556554 cites W2418802570 @default.
- W2024556554 doi "https://doi.org/10.1117/12.728283" @default.
- W2024556554 hasPublicationYear "2007" @default.
- W2024556554 type Work @default.
- W2024556554 sameAs 2024556554 @default.
- W2024556554 citedByCount "0" @default.
- W2024556554 crossrefType "proceedings-article" @default.
- W2024556554 hasAuthorship W2024556554A5020348826 @default.
- W2024556554 hasAuthorship W2024556554A5027637490 @default.
- W2024556554 hasAuthorship W2024556554A5038492659 @default.
- W2024556554 hasAuthorship W2024556554A5047000678 @default.
- W2024556554 hasAuthorship W2024556554A5074116993 @default.
- W2024556554 hasAuthorship W2024556554A5090064925 @default.
- W2024556554 hasConcept C104819515 @default.
- W2024556554 hasConcept C120665830 @default.
- W2024556554 hasConcept C121332964 @default.
- W2024556554 hasConcept C136009344 @default.
- W2024556554 hasConcept C136229726 @default.
- W2024556554 hasConcept C147080431 @default.
- W2024556554 hasConcept C155672457 @default.
- W2024556554 hasConcept C159985019 @default.
- W2024556554 hasConcept C171250308 @default.
- W2024556554 hasConcept C182606246 @default.
- W2024556554 hasConcept C192562407 @default.
- W2024556554 hasConcept C26771246 @default.
- W2024556554 hasConcept C2776502983 @default.
- W2024556554 hasConcept C2778818243 @default.
- W2024556554 hasConcept C2779178360 @default.
- W2024556554 hasConcept C33197981 @default.
- W2024556554 hasConcept C49040817 @default.
- W2024556554 hasConcept C71924100 @default.
- W2024556554 hasConcept C77017923 @default.
- W2024556554 hasConceptScore W2024556554C104819515 @default.
- W2024556554 hasConceptScore W2024556554C120665830 @default.
- W2024556554 hasConceptScore W2024556554C121332964 @default.
- W2024556554 hasConceptScore W2024556554C136009344 @default.
- W2024556554 hasConceptScore W2024556554C136229726 @default.
- W2024556554 hasConceptScore W2024556554C147080431 @default.
- W2024556554 hasConceptScore W2024556554C155672457 @default.
- W2024556554 hasConceptScore W2024556554C159985019 @default.
- W2024556554 hasConceptScore W2024556554C171250308 @default.
- W2024556554 hasConceptScore W2024556554C182606246 @default.
- W2024556554 hasConceptScore W2024556554C192562407 @default.
- W2024556554 hasConceptScore W2024556554C26771246 @default.
- W2024556554 hasConceptScore W2024556554C2776502983 @default.
- W2024556554 hasConceptScore W2024556554C2778818243 @default.
- W2024556554 hasConceptScore W2024556554C2779178360 @default.
- W2024556554 hasConceptScore W2024556554C33197981 @default.
- W2024556554 hasConceptScore W2024556554C49040817 @default.
- W2024556554 hasConceptScore W2024556554C71924100 @default.
- W2024556554 hasConceptScore W2024556554C77017923 @default.
- W2024556554 hasLocation W20245565541 @default.
- W2024556554 hasOpenAccess W2024556554 @default.
- W2024556554 hasPrimaryLocation W20245565541 @default.
- W2024556554 hasRelatedWork W2039564774 @default.
- W2024556554 hasRelatedWork W2052906622 @default.
- W2024556554 hasRelatedWork W2071957599 @default.
- W2024556554 hasRelatedWork W2077386682 @default.
- W2024556554 hasRelatedWork W2094066981 @default.
- W2024556554 hasRelatedWork W2094073750 @default.
- W2024556554 hasRelatedWork W2109791954 @default.
- W2024556554 hasRelatedWork W2151322789 @default.
- W2024556554 hasRelatedWork W2526896831 @default.
- W2024556554 hasRelatedWork W3195528049 @default.
- W2024556554 isParatext "false" @default.
- W2024556554 isRetracted "false" @default.
- W2024556554 magId "2024556554" @default.
- W2024556554 workType "article" @default.