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• W2024561353 abstract "Objective: Helicobacter pylori colonizes the gastric mucosa of about half of the world's population and it has been related to extragastrointestinal diseases. The present study sought to evaluate the association between H pylori infection and iron, zinc, and copper nutritional status in symptomatic children. Patients and Methods: A cross-sectional study was carried out in 395 children (4–16 years) with upper gastrointestinal symptoms, who were tested for H pylori infection by the 13C-urea breath test. Iron status was determined by hemoglobin, serum ferritin, and serum transferrin receptors. Copper and zinc serum concentrations were also evaluated. Epidemiological data, dietary assessment, and anthropometric indicators were analyzed as potential confounding factors. Results: Prevalence of H pylori infection was 24.3%. Anemia and iron deficiency (ID) were found in 12.0% and 14.3% of the H pylori–positive and 8.9% and 11.0% of the H pylori–negative children, respectively. There was no association between H pylori infection and anemia (odds ratio = 1.54 [95% confidence interval [CI] 0.73%–3.24%]) or ID (odds ratio = 1.35 [95% CI 0.67–2.70]). Crude β coefficients showed that H pylori has no significant effect on hemoglobin, serum ferritin, serum transferrin receptors, copper, and zinc concentrations. However, adjusted results suggested that H pylori–infected children had an increase of 9.74 μg/dL (95% CI 2.12–17.37 μg/dL) in copper concentrations. Conclusions: This study revealed that H pylori infection was not associated with iron deficiency, anemia, or zinc concentrations; however, a positive relation with copper status was found after adjusting for confounding factors. The contribution of H pylori infection to higher copper concentrations needs to be confirmed by additional studies." @default.
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• W2024561353 date "2010-07-01" @default.
• W2024561353 modified "2023-09-27" @default.
• W2024561353 title "Iron, Zinc, and Copper Nutritional Status in Children Infected With Helicobacter pylori" @default.
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• W2024561353 doi "https://doi.org/10.1097/mpg.0b013e3181c2c2cd" @default.
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