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- W2024573835 abstract "For two models of biological free-energy transducers, it is investigated how free-energy dissipation and efficiency vary as (i) the demand for output free energy, (ii) the input free energy or (iii) the properties of the transducers themselves, are varied. One model is representative of near-equilibrium free-energy transducers in general, the other is a special case of far-from-equilibrium free-energy transduction, reminiscent of proton pumping by bacteriorhodopsin. It turns out that the relationship between efficiency and free-energy dissipation depends strongly on what varies. In some cases, free-energy dissipation increases as the efficiency increases. It is suggested that this is one reason why biological evolution has not resulted in high efficiencies and low rates of free-energy dissipation. For the near-equilibrium free-energy transducer, the free-energy dissipation at the static head steady state is minimal with respect to variations in the output force. For the far-from-equilibrium model (of bacteriorhodopsin), the static head does not correspond to such a minimum, if that free-energy transducer slips." @default.
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- W2024573835 date "1987-10-01" @default.
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- W2024573835 title "Variation of efficiency with free-energy dissipation in models of biological energy transduction" @default.
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- W2024573835 doi "https://doi.org/10.1016/0301-4622(87)80072-8" @default.
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