Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024574832> ?p ?o ?g. }
- W2024574832 endingPage "125" @default.
- W2024574832 startingPage "111" @default.
- W2024574832 abstract "The genus Tokudaia comprises three species, two of which have lost their Y chromosome and have an XO/XO sex chromosome constitution. Although Tokudaia muenninki (Okinawa spiny rat) retains the Y chromosome, both sex chromosomes are unusually large. We conducted a molecular cytogenetic analysis to characterize the sex chromosomes of T. muenninki. Using cross-species fluorescence in situ hybridization (Zoo-FISH), we found that both short arms of the T. muenninki sex chromosomes were painted by probes from mouse chromosomes 11 and 16. Comparative genomic hybridization analysis was unable to detect sex-specific regions in the sex chromosomes because both sex probes highlighted the large heterochromatic blocks on the Y chromosome as well as five autosomal pairs. We then performed comparative FISH mapping using 29 mouse complementary DNA (cDNA) clones of the 22 X-linked genes and the seven genes linked to mouse chromosome 11 (whose homologue had fused to the sex chromosomes), and FISH mapping using two T. muenninki cDNA clones of the Y-linked genes. This analysis revealed that the ancestral gene order on the long arm of the X chromosome and the centromeric region of the short arm of the Y chromosome were conserved. Whereas six of the mouse chromosome 11 genes were also mapped to Xp and Yp, in addition, one gene, CBX2, was also mapped to Xp, Yp, and chromosome 14 in T. muenninki. CBX2 is the candidate gene for the novel sex determination system in the two other species of Tokudaia, which lack a Y chromosome and SRY gene. Overall, these results indicated that the Y chromosome of T. muenninki avoided a loss event, which occurred in an ancestral lineage of T. osimensis and T. tokunoshimensis, through fusion with an autosome. Despite retaining the Y chromosome, sex determination in T. muenninki might not follow the usual mammalian pattern and deserves further investigation." @default.
- W2024574832 created "2016-06-24" @default.
- W2024574832 creator A5000015993 @default.
- W2024574832 creator A5006817668 @default.
- W2024574832 creator A5019701232 @default.
- W2024574832 creator A5032674185 @default.
- W2024574832 creator A5045879266 @default.
- W2024574832 date "2011-12-24" @default.
- W2024574832 modified "2023-09-26" @default.
- W2024574832 title "The Y chromosome of the Okinawa spiny rat, Tokudaia muenninki, was rescued through fusion with an autosome" @default.
- W2024574832 cites W1508627934 @default.
- W2024574832 cites W1579872476 @default.
- W2024574832 cites W1583267914 @default.
- W2024574832 cites W1642105277 @default.
- W2024574832 cites W1964870136 @default.
- W2024574832 cites W1968080226 @default.
- W2024574832 cites W1973183858 @default.
- W2024574832 cites W1974525299 @default.
- W2024574832 cites W1976020359 @default.
- W2024574832 cites W1986163694 @default.
- W2024574832 cites W1998383188 @default.
- W2024574832 cites W2003232844 @default.
- W2024574832 cites W2005250311 @default.
- W2024574832 cites W2007969716 @default.
- W2024574832 cites W2009381014 @default.
- W2024574832 cites W2013246689 @default.
- W2024574832 cites W2014342578 @default.
- W2024574832 cites W2019591778 @default.
- W2024574832 cites W2020613289 @default.
- W2024574832 cites W2031380588 @default.
- W2024574832 cites W2032512363 @default.
- W2024574832 cites W2033505268 @default.
- W2024574832 cites W2037989494 @default.
- W2024574832 cites W2039811136 @default.
- W2024574832 cites W2043432920 @default.
- W2024574832 cites W2050172731 @default.
- W2024574832 cites W2053688874 @default.
- W2024574832 cites W2056942376 @default.
- W2024574832 cites W2060234119 @default.
- W2024574832 cites W2061311922 @default.
- W2024574832 cites W2080882866 @default.
- W2024574832 cites W2083061174 @default.
- W2024574832 cites W2087159185 @default.
- W2024574832 cites W2089159455 @default.
- W2024574832 cites W2092738781 @default.
- W2024574832 cites W2115180090 @default.
- W2024574832 cites W2115570902 @default.
- W2024574832 cites W2116412804 @default.
- W2024574832 cites W2124405628 @default.
- W2024574832 cites W2129563579 @default.
- W2024574832 cites W2142602296 @default.
- W2024574832 cites W2166299699 @default.
- W2024574832 cites W2167952426 @default.
- W2024574832 cites W2170806212 @default.
- W2024574832 cites W4229487902 @default.
- W2024574832 doi "https://doi.org/10.1007/s10577-011-9268-6" @default.
- W2024574832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22198613" @default.
- W2024574832 hasPublicationYear "2011" @default.
- W2024574832 type Work @default.
- W2024574832 sameAs 2024574832 @default.
- W2024574832 citedByCount "25" @default.
- W2024574832 countsByYear W20245748322012 @default.
- W2024574832 countsByYear W20245748322013 @default.
- W2024574832 countsByYear W20245748322014 @default.
- W2024574832 countsByYear W20245748322015 @default.
- W2024574832 countsByYear W20245748322016 @default.
- W2024574832 countsByYear W20245748322017 @default.
- W2024574832 countsByYear W20245748322018 @default.
- W2024574832 countsByYear W20245748322019 @default.
- W2024574832 countsByYear W20245748322020 @default.
- W2024574832 countsByYear W20245748322021 @default.
- W2024574832 countsByYear W20245748322022 @default.
- W2024574832 countsByYear W20245748322023 @default.
- W2024574832 crossrefType "journal-article" @default.
- W2024574832 hasAuthorship W2024574832A5000015993 @default.
- W2024574832 hasAuthorship W2024574832A5006817668 @default.
- W2024574832 hasAuthorship W2024574832A5019701232 @default.
- W2024574832 hasAuthorship W2024574832A5032674185 @default.
- W2024574832 hasAuthorship W2024574832A5045879266 @default.
- W2024574832 hasBestOaLocation W20245748321 @default.
- W2024574832 hasConcept C103435993 @default.
- W2024574832 hasConcept C104317684 @default.
- W2024574832 hasConcept C134925867 @default.
- W2024574832 hasConcept C137555145 @default.
- W2024574832 hasConcept C153911025 @default.
- W2024574832 hasConcept C163588314 @default.
- W2024574832 hasConcept C167752854 @default.
- W2024574832 hasConcept C2777542201 @default.
- W2024574832 hasConcept C2780246931 @default.
- W2024574832 hasConcept C30481170 @default.
- W2024574832 hasConcept C35158069 @default.
- W2024574832 hasConcept C54355233 @default.
- W2024574832 hasConcept C54815482 @default.
- W2024574832 hasConcept C73456138 @default.
- W2024574832 hasConcept C86803240 @default.
- W2024574832 hasConceptScore W2024574832C103435993 @default.
- W2024574832 hasConceptScore W2024574832C104317684 @default.
- W2024574832 hasConceptScore W2024574832C134925867 @default.