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- W2024579562 abstract "A highly stereoselective, enzymatic reduction of an α-chloro-β-keto ester provided the key intermediate for a total synthesis of the α-hydroxy-β-amino acid moiety of (−)-bestatin. The reduction product was cyclized to a glycidic ester that was opened in a Ritter reaction with benzonitrile, affording a trans-oxazoline, which was hydrolyzed under acidic conditions to the target molecule." @default.
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- W2024579562 date "2005-09-01" @default.
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- W2024579562 title "Chemoenzymatic formal total synthesis of (−)-bestatin" @default.
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- W2024579562 doi "https://doi.org/10.1016/j.tetasy.2005.08.022" @default.
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