Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024588503> ?p ?o ?g. }
- W2024588503 endingPage "1063" @default.
- W2024588503 startingPage "1058" @default.
- W2024588503 abstract "Budding yeast noncoding RNAs (ncRNAs) are pervasively transcribed during mitosis, and some regulate mitotic protein-coding genes. However, little is known about ncRNA expression during meiotic development. Using high-resolution profiling we identified an extensive meiotic ncRNA expression program interlaced with the protein-coding transcriptome via sense/antisense transcript pairs, bidirectional promoters, and ncRNAs that overlap the regulatory regions of genes. Meiotic unannotated transcripts (MUTs) are mitotic targets of the conserved exosome component Rrp6, which itself is degraded after the onset of meiosis when MUTs and other ncRNAs accumulate in successive waves. Diploid cells lacking Rrp6 fail to initiate premeiotic DNA replication normally and cannot undergo efficient meiotic development. The present study demonstrates a unique function for budding yeast Rrp6 in degrading distinct classes of meiotically induced ncRNAs during vegetative growth and the onset of meiosis and thus points to a critical role of differential ncRNA expression in the execution of a conserved developmental program." @default.
- W2024588503 created "2016-06-24" @default.
- W2024588503 creator A5002497731 @default.
- W2024588503 creator A5015996736 @default.
- W2024588503 creator A5021418585 @default.
- W2024588503 creator A5022830611 @default.
- W2024588503 creator A5034202632 @default.
- W2024588503 creator A5036715969 @default.
- W2024588503 creator A5065603458 @default.
- W2024588503 creator A5068379805 @default.
- W2024588503 creator A5071252885 @default.
- W2024588503 creator A5079640569 @default.
- W2024588503 date "2010-12-13" @default.
- W2024588503 modified "2023-10-18" @default.
- W2024588503 title "Execution of the meiotic noncoding RNA expression program and the onset of gametogenesis in yeast require the conserved exosome subunit Rrp6" @default.
- W2024588503 cites W1517816201 @default.
- W2024588503 cites W1575910125 @default.
- W2024588503 cites W1857142138 @default.
- W2024588503 cites W1963604994 @default.
- W2024588503 cites W1968055625 @default.
- W2024588503 cites W1969636175 @default.
- W2024588503 cites W1978856165 @default.
- W2024588503 cites W1978967539 @default.
- W2024588503 cites W1979952533 @default.
- W2024588503 cites W1983373109 @default.
- W2024588503 cites W1988952096 @default.
- W2024588503 cites W1991356071 @default.
- W2024588503 cites W1991866946 @default.
- W2024588503 cites W2005964372 @default.
- W2024588503 cites W2008616402 @default.
- W2024588503 cites W2021314556 @default.
- W2024588503 cites W2027950141 @default.
- W2024588503 cites W2028513775 @default.
- W2024588503 cites W2028845769 @default.
- W2024588503 cites W2032501207 @default.
- W2024588503 cites W2034023446 @default.
- W2024588503 cites W2037451497 @default.
- W2024588503 cites W2037877965 @default.
- W2024588503 cites W2040378600 @default.
- W2024588503 cites W2041728027 @default.
- W2024588503 cites W2047765648 @default.
- W2024588503 cites W2054229788 @default.
- W2024588503 cites W2060297364 @default.
- W2024588503 cites W2067659875 @default.
- W2024588503 cites W2087377443 @default.
- W2024588503 cites W2106311348 @default.
- W2024588503 cites W2107002447 @default.
- W2024588503 cites W2109635944 @default.
- W2024588503 cites W2123712380 @default.
- W2024588503 cites W2128223017 @default.
- W2024588503 cites W2128349391 @default.
- W2024588503 cites W2129232563 @default.
- W2024588503 cites W2134597218 @default.
- W2024588503 cites W2135951244 @default.
- W2024588503 cites W2140022443 @default.
- W2024588503 cites W2148600978 @default.
- W2024588503 cites W2150014428 @default.
- W2024588503 cites W2151695982 @default.
- W2024588503 cites W2152646714 @default.
- W2024588503 cites W2153222734 @default.
- W2024588503 cites W2160689765 @default.
- W2024588503 cites W2165969644 @default.
- W2024588503 doi "https://doi.org/10.1073/pnas.1016459108" @default.
- W2024588503 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3024698" @default.
- W2024588503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21149693" @default.
- W2024588503 hasPublicationYear "2010" @default.
- W2024588503 type Work @default.
- W2024588503 sameAs 2024588503 @default.
- W2024588503 citedByCount "124" @default.
- W2024588503 countsByYear W20245885032012 @default.
- W2024588503 countsByYear W20245885032013 @default.
- W2024588503 countsByYear W20245885032014 @default.
- W2024588503 countsByYear W20245885032015 @default.
- W2024588503 countsByYear W20245885032016 @default.
- W2024588503 countsByYear W20245885032017 @default.
- W2024588503 countsByYear W20245885032018 @default.
- W2024588503 countsByYear W20245885032019 @default.
- W2024588503 countsByYear W20245885032020 @default.
- W2024588503 countsByYear W20245885032021 @default.
- W2024588503 countsByYear W20245885032022 @default.
- W2024588503 countsByYear W20245885032023 @default.
- W2024588503 crossrefType "journal-article" @default.
- W2024588503 hasAuthorship W2024588503A5002497731 @default.
- W2024588503 hasAuthorship W2024588503A5015996736 @default.
- W2024588503 hasAuthorship W2024588503A5021418585 @default.
- W2024588503 hasAuthorship W2024588503A5022830611 @default.
- W2024588503 hasAuthorship W2024588503A5034202632 @default.
- W2024588503 hasAuthorship W2024588503A5036715969 @default.
- W2024588503 hasAuthorship W2024588503A5065603458 @default.
- W2024588503 hasAuthorship W2024588503A5068379805 @default.
- W2024588503 hasAuthorship W2024588503A5071252885 @default.
- W2024588503 hasAuthorship W2024588503A5079640569 @default.
- W2024588503 hasBestOaLocation W20245885031 @default.
- W2024588503 hasConcept C104317684 @default.
- W2024588503 hasConcept C148196450 @default.
- W2024588503 hasConcept C194993378 @default.
- W2024588503 hasConcept C2777576037 @default.
- W2024588503 hasConcept C54355233 @default.