FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024588527> ?p ?o ?g. }

• W2024588527 endingPage "2003" @default.
• W2024588527 startingPage "1997" @default.
• W2024588527 abstract "There is a lack of information on how individual microsatellite loci differ with respect to their mutation properties. Such variation will have an important bearing on our understanding of the ubiquitous occurrence of simple repeat sequences in eukaryotic genomes and on deriving proper mutation models that can be incorporated into genetic distance estimates. We genotyped approximately 100 families of the bird barn swallow (Hirundo rustica) for two hypervariable (heterozygosity >95%) microsatellite markers: HrU6, an (AAAG)n tetranucleotide repeat, and HrU10, an (AAGAG)n pentanucleotide repeat. A total of 27 germline mutation events were documented, corresponding to mutation rates of 0.57% (HrU6) and 1.56% (HrU10). The mutation rate increased with allele size, at approximately 0.1% per repeat unit over the observed range of allele sizes (approximately 10-100 repeat units). Single repeat unit changes dominated, with 21/27 mutations representing the gain or loss of one repeat unit. There was no clear difference in the number of gains versus losses nor was there an effect of allele size on the magnitude or direction of mutation. Unexpectedly, the mutation rate of females (maternally transmitted mutations) was 2.5-5 times higher than that of males. Contrasting these observations with mutation data from other microsatellite loci reveals differences not only in the mutation rate, but also in the magnitude, direction and effect of sex on mutation. Thus, microsatellite mutation and evolution may be viewed as a dynamic and variable process." @default.
• W2024588527 created "2016-06-24" @default.
• W2024588527 creator A5032121794 @default.
• W2024588527 creator A5039382493 @default.
• W2024588527 creator A5073922372 @default.
• W2024588527 creator A5078574186 @default.
• W2024588527 date "2002-05-01" @default.
• W2024588527 modified "2023-10-17" @default.
• W2024588527 title "Heterogeneity in the rate and pattern of germline mutation at individual microsatellite loci" @default.
• W2024588527 cites W1528307809 @default.
• W2024588527 cites W1562097577 @default.
• W2024588527 cites W1771404712 @default.
• W2024588527 cites W1827209629 @default.
• W2024588527 cites W1829226058 @default.
• W2024588527 cites W1935763178 @default.
• W2024588527 cites W1945353891 @default.
• W2024588527 cites W1965265115 @default.
• W2024588527 cites W1970114035 @default.
• W2024588527 cites W1975644140 @default.
• W2024588527 cites W1981416797 @default.
• W2024588527 cites W1984104678 @default.
• W2024588527 cites W1984470203 @default.
• W2024588527 cites W1985242213 @default.
• W2024588527 cites W1990284991 @default.
• W2024588527 cites W2005571101 @default.
• W2024588527 cites W2011719683 @default.
• W2024588527 cites W2040657452 @default.
• W2024588527 cites W2061941091 @default.
• W2024588527 cites W2063362959 @default.
• W2024588527 cites W2064692111 @default.
• W2024588527 cites W2067420735 @default.
• W2024588527 cites W2086057335 @default.
• W2024588527 cites W2090223604 @default.
• W2024588527 cites W2102693380 @default.
• W2024588527 cites W2112066577 @default.
• W2024588527 cites W2122760250 @default.
• W2024588527 cites W2128517392 @default.
• W2024588527 cites W2131426370 @default.
• W2024588527 cites W2136275044 @default.
• W2024588527 cites W2140657958 @default.
• W2024588527 cites W2142710492 @default.
• W2024588527 cites W2146168345 @default.
• W2024588527 cites W2154782029 @default.
• W2024588527 cites W2156380818 @default.
• W2024588527 cites W2161489087 @default.
• W2024588527 cites W2162330784 @default.
• W2024588527 cites W2164109844 @default.
• W2024588527 cites W2334247097 @default.
• W2024588527 doi "https://doi.org/10.1093/nar/30.9.1997" @default.
• W2024588527 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/113841" @default.
• W2024588527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11972338" @default.
• W2024588527 hasPublicationYear "2002" @default.
• W2024588527 type Work @default.
• W2024588527 sameAs 2024588527 @default.
• W2024588527 citedByCount "84" @default.
• W2024588527 countsByYear W20245885272012 @default.
• W2024588527 countsByYear W20245885272013 @default.
• W2024588527 countsByYear W20245885272014 @default.
• W2024588527 countsByYear W20245885272015 @default.
• W2024588527 countsByYear W20245885272017 @default.
• W2024588527 countsByYear W20245885272018 @default.
• W2024588527 countsByYear W20245885272019 @default.
• W2024588527 countsByYear W20245885272020 @default.
• W2024588527 countsByYear W20245885272021 @default.
• W2024588527 crossrefType "journal-article" @default.
• W2024588527 hasAuthorship W2024588527A5032121794 @default.
• W2024588527 hasAuthorship W2024588527A5039382493 @default.
• W2024588527 hasAuthorship W2024588527A5073922372 @default.
• W2024588527 hasAuthorship W2024588527A5078574186 @default.
• W2024588527 hasBestOaLocation W20245885271 @default.
• W2024588527 hasConcept C104317684 @default.
• W2024588527 hasConcept C13514818 @default.
• W2024588527 hasConcept C143589142 @default.
• W2024588527 hasConcept C180754005 @default.
• W2024588527 hasConcept C2910240311 @default.
• W2024588527 hasConcept C501734568 @default.
• W2024588527 hasConcept C54355233 @default.
• W2024588527 hasConcept C61320498 @default.
• W2024588527 hasConcept C86803240 @default.
• W2024588527 hasConcept C98638677 @default.
• W2024588527 hasConceptScore W2024588527C104317684 @default.
• W2024588527 hasConceptScore W2024588527C13514818 @default.
• W2024588527 hasConceptScore W2024588527C143589142 @default.
• W2024588527 hasConceptScore W2024588527C180754005 @default.
• W2024588527 hasConceptScore W2024588527C2910240311 @default.
• W2024588527 hasConceptScore W2024588527C501734568 @default.
• W2024588527 hasConceptScore W2024588527C54355233 @default.
• W2024588527 hasConceptScore W2024588527C61320498 @default.
• W2024588527 hasConceptScore W2024588527C86803240 @default.
• W2024588527 hasConceptScore W2024588527C98638677 @default.
• W2024588527 hasIssue "9" @default.
• W2024588527 hasLocation W20245885271 @default.
• W2024588527 hasLocation W20245885272 @default.
• W2024588527 hasLocation W20245885273 @default.
• W2024588527 hasLocation W20245885274 @default.
• W2024588527 hasOpenAccess W2024588527 @default.
• W2024588527 hasPrimaryLocation W20245885271 @default.
• W2024588527 hasRelatedWork W2024588527 @default.

• next