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- W2024591784 abstract "Bis(alpha-furancarboxylato)oxovanadium(IV)--a new orally active antidiabetic vanadyl complex has been synthesized, characterized, and tested for bioactivity as insulin-enhancing agents. The complex was administered intragastrically to both normal and STZ-diabetic rats for 4 weeks. The results show that the complex at a dose of 10.0 and 20.0 mg V kg(-1), could significantly lower the blood glucose level rats and ameliorated impaired glucose tolerance in STZ-diabetic, but not in normal rats. It was suggested that the complex exerted an antidiabetic effect in STZ-diabetic rats, which maybe was related to increasing the sensitivity to insulin." @default.
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- W2024591784 date "2005-02-01" @default.
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- W2024591784 title "A new orally active antidiabetic vanadyl complex – bis(α-furancarboxylato)oxovanadium(IV)" @default.
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- W2024591784 doi "https://doi.org/10.1016/j.jinorgbio.2004.10.033" @default.
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