Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024608002> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2024608002 endingPage "20" @default.
- W2024608002 startingPage "17" @default.
- W2024608002 abstract "To study the mechanism of hormonal regulation of the 25‐hydroxyvitamin D 24‐hydroxylase, a DNA probe complementary to the published sequence of the recently cloned P450 component [(1991) FEBS Lett. 278, 195] was employed. Young (2 month) and adult (12 month) F344 rats, deficient in 1,25‐dihydroxyvitamin D, were given a single dose or 1,25‐dihydroxyvitamin D. In young rats, 1,25‐dihydroxyvitamin D markedly increased P450 mRNA levels within 3 h in both kidney and intestine, and maximal levels were attained at 16 and 3 h, respectively. In adult animals, maximal induction of mRNA was diminished in the kidney, and the decline was slower in the intestine. Time of maximal induction did not change with age. These studies demonstrate for the first time regulation of the 24‐hydroxylase enzyme by 1,25‐dihydroxyvitamin D at the level ofthe mRNA for the cytochrome P450. They also demonstrate that this regulation may change with age." @default.
- W2024608002 created "2016-06-24" @default.
- W2024608002 date "1991-11-04" @default.
- W2024608002 modified "2023-10-15" @default.
- W2024608002 title "Expression of 25‐hydroxyvitamin D 24‐hydroxylase cytochrome P450 in kidney and intestine Effect of 1,25‐dihydroxyvitamin D and age" @default.
- W2024608002 cites W1564126555 @default.
- W2024608002 cites W1579204819 @default.
- W2024608002 cites W1600330543 @default.
- W2024608002 cites W1968596816 @default.
- W2024608002 cites W1972737190 @default.
- W2024608002 cites W1972829107 @default.
- W2024608002 cites W2004905036 @default.
- W2024608002 cites W2057112465 @default.
- W2024608002 cites W2125701765 @default.
- W2024608002 cites W2144177308 @default.
- W2024608002 cites W2180215713 @default.
- W2024608002 cites W2322804362 @default.
- W2024608002 cites W49403671 @default.
- W2024608002 doi "https://doi.org/10.1016/0014-5793(91)80823-l" @default.
- W2024608002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1959602" @default.
- W2024608002 hasPublicationYear "1991" @default.
- W2024608002 type Work @default.
- W2024608002 sameAs 2024608002 @default.
- W2024608002 citedByCount "51" @default.
- W2024608002 countsByYear W20246080022012 @default.
- W2024608002 countsByYear W20246080022013 @default.
- W2024608002 countsByYear W20246080022014 @default.
- W2024608002 countsByYear W20246080022018 @default.
- W2024608002 countsByYear W20246080022021 @default.
- W2024608002 crossrefType "journal-article" @default.
- W2024608002 hasBestOaLocation W20246080021 @default.
- W2024608002 hasConcept C104317684 @default.
- W2024608002 hasConcept C105580179 @default.
- W2024608002 hasConcept C126322002 @default.
- W2024608002 hasConcept C134018914 @default.
- W2024608002 hasConcept C185592680 @default.
- W2024608002 hasConcept C2780091579 @default.
- W2024608002 hasConcept C526171541 @default.
- W2024608002 hasConcept C55493867 @default.
- W2024608002 hasConcept C62231903 @default.
- W2024608002 hasConcept C71315377 @default.
- W2024608002 hasConcept C71924100 @default.
- W2024608002 hasConcept C86803240 @default.
- W2024608002 hasConceptScore W2024608002C104317684 @default.
- W2024608002 hasConceptScore W2024608002C105580179 @default.
- W2024608002 hasConceptScore W2024608002C126322002 @default.
- W2024608002 hasConceptScore W2024608002C134018914 @default.
- W2024608002 hasConceptScore W2024608002C185592680 @default.
- W2024608002 hasConceptScore W2024608002C2780091579 @default.
- W2024608002 hasConceptScore W2024608002C526171541 @default.
- W2024608002 hasConceptScore W2024608002C55493867 @default.
- W2024608002 hasConceptScore W2024608002C62231903 @default.
- W2024608002 hasConceptScore W2024608002C71315377 @default.
- W2024608002 hasConceptScore W2024608002C71924100 @default.
- W2024608002 hasConceptScore W2024608002C86803240 @default.
- W2024608002 hasIssue "1-2" @default.
- W2024608002 hasLocation W20246080021 @default.
- W2024608002 hasLocation W20246080022 @default.
- W2024608002 hasOpenAccess W2024608002 @default.
- W2024608002 hasPrimaryLocation W20246080021 @default.
- W2024608002 hasRelatedWork W1966504330 @default.
- W2024608002 hasRelatedWork W1972779667 @default.
- W2024608002 hasRelatedWork W1979139803 @default.
- W2024608002 hasRelatedWork W1984079239 @default.
- W2024608002 hasRelatedWork W1991560548 @default.
- W2024608002 hasRelatedWork W2037631372 @default.
- W2024608002 hasRelatedWork W2040058909 @default.
- W2024608002 hasRelatedWork W2086651592 @default.
- W2024608002 hasRelatedWork W2132898409 @default.
- W2024608002 hasRelatedWork W2748952813 @default.
- W2024608002 hasVolume "292" @default.
- W2024608002 isParatext "false" @default.
- W2024608002 isRetracted "false" @default.
- W2024608002 magId "2024608002" @default.
- W2024608002 workType "article" @default.