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• W2024633337 abstract "A constituent of cow's milk, bovine serum albumin (BSA), has recently been implicated as a possible trigger of insulin-dependent diabetes mellitus (IDDM) ( 1. Karjalainen J Martin JM Knip M Ilonen J Robinson BH Savilahti E Akerblom HD Dosch HM A bovine albumin peptide as a possible trigger of insulin-dependent diabetes mellitus. N Engl J Med. 1992; 327: 302-307 Google Scholar ). Levels of serum antibodies to BSA were significantly elevated in children newly diagnosed with diabetes compared with normal control subjects ( 1. Karjalainen J Martin JM Knip M Ilonen J Robinson BH Savilahti E Akerblom HD Dosch HM A bovine albumin peptide as a possible trigger of insulin-dependent diabetes mellitus. N Engl J Med. 1992; 327: 302-307 Google Scholar , 2. Savilahti E Akerblom HK Tainio VM Koskimies S Children with newly diagnosed insulin-dependent diabetes mellitus have increased levels of cow's milk antibodies. Diabetes Res. 1888; 7: 137-140 Google Scholar ), and cow's milk protein was diabetogenic in animal models of IDDM ( 3. Elliott RB Martin JM Dietary protein: a trigger of insulin-dependent diabetes in the BB rat?. Diabetologia. 1984; 26: 297-299 Google Scholar , 4. Daneman D Fishman L Clarson C Martin JM Dietary triggers of insulin-dependent diabetes in the BB rat. Diabetes Res. 1987; 5: 93-97 Google Scholar ). In the latter studies, rats fed cow's milk protein at the onset of weaning (day 13) had an incidence of diabetes 2.6-fold greater than animals receiving milk-free protein during weaning and milk protein after weaning (day 23) ( 4. Daneman D Fishman L Clarson C Martin JM Dietary triggers of insulin-dependent diabetes in the BB rat. Diabetes Res. 1987; 5: 93-97 Google Scholar ). A Finnish study demonstrated that children who were older than 4 months of age when supplementary feeding (food or formula) was started had a lower risk of IDDM than those whose diets were supplemented before this age ( 5. Virtanen SM Rasanen L Aro A Infant feeding in Finnish children <7 years of age with newly diagnosed IDDM. Diabetes Care. 1991; 14: 415-417 Google Scholar ). Hence, there may be a window of time in early infancy when the consumption of cow's milk protein raises the risk for later development of IDDM." @default.
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• W2024633337 title "Bovine serum albumin detected in infant formula is a possible trigger for insulin-dependent diabetes mellitus" @default.
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• W2024633337 doi "https://doi.org/10.1016/0002-8223(94)90376-x" @default.
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