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• W2024640018 abstract "The condensation cyclization between isatins and 5-methoxy tryptamine catalyzed by chiral phosphoric acids provides spirooxindole tetrahydro-β-carboline products in excellent yields (up to 99%) and enantioselectivity (up to 98:2 er). A comparison of catalysts provides insight for the substrate scope and factors responsible for efficient catalytic activity and selectivity in the spirocyclization. Chiral phosphoric acids with different 3,3′-substitution on the binaphthyl system and opposite axial chirality afford the spiroindolone product with the same absolute configuration." @default.
• W2024640018 created "2016-06-24" @default.
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• W2024640018 date "2011-10-01" @default.
• W2024640018 modified "2023-10-18" @default.
• W2024640018 title "Enantioselective Pictet–Spengler reactions of isatins for the synthesis of spiroindolones" @default.
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• W2024640018 doi "https://doi.org/10.1016/j.tetlet.2011.08.071" @default.
• W2024640018 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3307811" @default.
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