FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024641034> ?p ?o ?g. }

• W2024641034 endingPage "610" @default.
• W2024641034 startingPage "602" @default.
• W2024641034 abstract "Objectives/Hypothesis Oxandrolone (Ox) increases height gain but may also cause voice deepening in growth hormone (GH)-treated girls with Turner syndrome (TS). We assessed the effect of Ox on objective and subjective speaking voice frequency in GH-treated girls with TS. Study Design A multicenter, randomized, placebo (Pl)-controlled, double-blind study was conducted. Methods One hundred thirty-three patients were included and treated with GH (1.33 mg/m2/d) from baseline, combined with Pl or Ox in a low (0.03 mg/kg/d) or conventional (0.06 mg/kg/d) dose from the age of 8 years and estrogens from the age of 12 years. Yearly from starting Ox/Pl until 6 months after discontinuing GH+Ox/Pl, voices were recorded and questionnaires were completed. Results At start, mean (±standard deviation [SD]) voice frequency SD score (SDS) was high for age (1.0±1.2, P<0.001) but normal for height. Compared with GH+Pl, voices tended to lower on GH+Ox 0.03 (P=0.09) and significantly lowered on GH+Ox 0.06 (P=0.007). At the last measurement, voice frequency SDS was still relatively high in GH+Pl group (0.6±0.7, P=0.002) but similar to healthy girls in both GH+Ox groups. Voice frequency became lower than −2 SDS in one patient (3%) on GH+Ox 0.03 and three patients (11%) on GH+Ox 0.06. The percentage of patients reporting subjective voice deepening was similar between the dosage groups. Conclusions Untreated girls with TS have relatively high-pitched voices. The addition of Ox to GH decreases voice frequency in a dose-dependent way. Although most voice frequencies remain within the normal range, they may occasionally become lower than −2 SDS, especially on GH+Ox 0.06 mg/kg/d." @default.
• W2024641034 created "2016-06-24" @default.
• W2024641034 creator A5001885812 @default.
• W2024641034 creator A5002337289 @default.
• W2024641034 creator A5004559761 @default.
• W2024641034 creator A5004858830 @default.
• W2024641034 creator A5013809975 @default.
• W2024641034 creator A5054571302 @default.
• W2024641034 creator A5065362953 @default.
• W2024641034 creator A5068604873 @default.
• W2024641034 creator A5077147119 @default.
• W2024641034 creator A5084590869 @default.
• W2024641034 date "2011-09-01" @default.
• W2024641034 modified "2023-09-26" @default.
• W2024641034 title "The Effect of Oxandrolone on Voice Frequency in Growth Hormone-Treated Girls With Turner Syndrome" @default.
• W2024641034 cites W1608143314 @default.
• W2024641034 cites W1967340679 @default.
• W2024641034 cites W1980982708 @default.
• W2024641034 cites W1998576835 @default.
• W2024641034 cites W1999541442 @default.
• W2024641034 cites W2002642271 @default.
• W2024641034 cites W2005045984 @default.
• W2024641034 cites W2005759400 @default.
• W2024641034 cites W2013492072 @default.
• W2024641034 cites W2014448826 @default.
• W2024641034 cites W2033287940 @default.
• W2024641034 cites W2037772682 @default.
• W2024641034 cites W2040039196 @default.
• W2024641034 cites W2050566341 @default.
• W2024641034 cites W2061326594 @default.
• W2024641034 cites W2071114725 @default.
• W2024641034 cites W2081983661 @default.
• W2024641034 cites W2083931900 @default.
• W2024641034 cites W2090390768 @default.
• W2024641034 cites W2090621101 @default.
• W2024641034 cites W2109352311 @default.
• W2024641034 cites W2110066552 @default.
• W2024641034 cites W2123947372 @default.
• W2024641034 cites W2129595192 @default.
• W2024641034 cites W2147133969 @default.
• W2024641034 cites W2166383227 @default.
• W2024641034 cites W2171589158 @default.
• W2024641034 cites W4243078586 @default.
• W2024641034 cites W99744298 @default.
• W2024641034 doi "https://doi.org/10.1016/j.jvoice.2010.06.002" @default.
• W2024641034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20971614" @default.
• W2024641034 hasPublicationYear "2011" @default.
• W2024641034 type Work @default.
• W2024641034 sameAs 2024641034 @default.
• W2024641034 citedByCount "11" @default.
• W2024641034 countsByYear W20246410342013 @default.
• W2024641034 countsByYear W20246410342014 @default.
• W2024641034 countsByYear W20246410342015 @default.
• W2024641034 countsByYear W20246410342016 @default.
• W2024641034 countsByYear W20246410342018 @default.
• W2024641034 countsByYear W20246410342019 @default.
• W2024641034 countsByYear W20246410342021 @default.
• W2024641034 countsByYear W20246410342022 @default.
• W2024641034 crossrefType "journal-article" @default.
• W2024641034 hasAuthorship W2024641034A5001885812 @default.
• W2024641034 hasAuthorship W2024641034A5002337289 @default.
• W2024641034 hasAuthorship W2024641034A5004559761 @default.
• W2024641034 hasAuthorship W2024641034A5004858830 @default.
• W2024641034 hasAuthorship W2024641034A5013809975 @default.
• W2024641034 hasAuthorship W2024641034A5054571302 @default.
• W2024641034 hasAuthorship W2024641034A5065362953 @default.
• W2024641034 hasAuthorship W2024641034A5068604873 @default.
• W2024641034 hasAuthorship W2024641034A5077147119 @default.
• W2024641034 hasAuthorship W2024641034A5084590869 @default.
• W2024641034 hasConcept C126322002 @default.
• W2024641034 hasConcept C134018914 @default.
• W2024641034 hasConcept C142724271 @default.
• W2024641034 hasConcept C204787440 @default.
• W2024641034 hasConcept C27081682 @default.
• W2024641034 hasConcept C2779683239 @default.
• W2024641034 hasConcept C2779733885 @default.
• W2024641034 hasConcept C2984496839 @default.
• W2024641034 hasConcept C71315377 @default.
• W2024641034 hasConcept C71924100 @default.
• W2024641034 hasConceptScore W2024641034C126322002 @default.
• W2024641034 hasConceptScore W2024641034C134018914 @default.
• W2024641034 hasConceptScore W2024641034C142724271 @default.
• W2024641034 hasConceptScore W2024641034C204787440 @default.
• W2024641034 hasConceptScore W2024641034C27081682 @default.
• W2024641034 hasConceptScore W2024641034C2779683239 @default.
• W2024641034 hasConceptScore W2024641034C2779733885 @default.
• W2024641034 hasConceptScore W2024641034C2984496839 @default.
• W2024641034 hasConceptScore W2024641034C71315377 @default.
• W2024641034 hasConceptScore W2024641034C71924100 @default.
• W2024641034 hasFunder F4320307758 @default.
• W2024641034 hasFunder F4320307765 @default.
• W2024641034 hasIssue "5" @default.
• W2024641034 hasLocation W20246410341 @default.
• W2024641034 hasLocation W20246410342 @default.
• W2024641034 hasOpenAccess W2024641034 @default.
• W2024641034 hasPrimaryLocation W20246410341 @default.
• W2024641034 hasRelatedWork W1984614377 @default.
• W2024641034 hasRelatedWork W1997759048 @default.

• next